Activity, toxicity and analysis of resistance of essential oil from Chenopodium ambrosioides after intraperitoneal, oral and intralesional administration in BALB/c mice infected with Leishmania amazonensis: A preliminary study

Monzote, Lianet; Montalvo, Ana Margarita; Scull, Ramón; Martínez, Migdalia Miranda; Abreu, Juan

doi:10.1016/j.biopha.2006.12.001

Cited by 47 publications

(32 citation statements)

References 22 publications

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“…This suggests that cinnamon oil has similar antimicrobial activity against planktonic bacteria and bacteria in biofilms. In addition, another advantage of the use of essentials oil over antibiotics may be that bacteria do not develop resistance to essential oils (29). The present study showed that cinnamon oil has synergistic activity with chlorhexidine, triclosan, and gentamicin except for strains that are resistant against triclosan or gentamicin.…”

Section: Discussionmentioning

confidence: 48%

Effect of Cinnamon Oil on icaA Expression and Biofilm Formation by Staphylococcus epidermidis

Nuryastuti

Mei

Busscher

et al. 2009

Appl Environ Microbiol

131

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Staphylococcus epidermidis is notorious for its biofilm formation on medical devices, and novel approaches to prevent and kill S. epidermidis biofilms are desired. In this study, the effect of cinnamon oil on planktonic and biofilm cultures of clinical S. epidermidis isolates was evaluated. Initially, susceptibility to cinnamon oil in planktonic cultures was compared to the commonly used antimicrobial agents chlorhexidine, triclosan, and gentamicin. The MIC of cinnamon oil, defined as the lowest concentration able to inhibit visible microbial growth, and the minimal bactericidal concentration, the lowest concentration required to kill 99.9% of the bacteria, were determined using the broth microdilution method and plating on agar. A checkerboard assay was used to evaluate the possible synergy between cinnamon oil and the other antimicrobial agents. The effect of cinnamon oil on biofilm growth was studied in 96-well plates and with confocal laser-scanning microscopy (CLSM). Biofilm susceptibility was determined using a metabolic 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay. Real-time PCR analysis was performed to determine the effect of sub-MIC concentrations of cinnamon oil on expression of the biofilm-related gene, icaA. Cinnamon oil showed antimicrobial activity against both planktonic and biofilm cultures of clinical S. epidermidis strains. There was only a small difference between planktonic and biofilm MICs, ranging from 0.5 to 1% and 1 to 2%, respectively. CLSM images indicated that cinnamon oil is able to detach and kill existing biofilms. Thus, cinnamon oil is an effective antimicrobial agent to combat S. epidermidis biofilms.

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Section: Discussionmentioning

confidence: 48%

Effect of Cinnamon Oil on icaA Expression and Biofilm Formation by Staphylococcus epidermidis

Nuryastuti

Mei

Busscher

et al. 2009

Appl Environ Microbiol

131

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“…Plants and their natural products constitute good sources of interesting lead compounds that could be potentially active against Leishmania or Trypanosoma (Croft et al 2005). Essential oils from aromatic plants such as Chenopodium ambrosioides (Monzote et al 2007), Origanum vulgare, Thymus vulgaris (Santoro et al 2007b), Melissa officinalis (Mikus et al 2000), Ocimum gratissimum (Ueda-Nakamura et al 2006), Salvia cilicica (Tan et al 2002), Salvia gilliessi (Sanchez et al 2006), Rosmarinus officinalis (Braga et al 2007) and Croton cajucara (Euphorbiaceae) (Rosa et al 2003) have been found to be effective against Leish- …”

mentioning

confidence: 99%

Chemical composition and antiprotozoal activities of Colombian Lippia spp essential oils and their major components

Escobar

Pinto

Herrera

et al. 2010

Mem. Inst. Oswaldo Cruz

155

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“…This species is American in origin and has a characteristic aroma (De Santayana et al, 2005); it is used as dietary condiments and as traditional medicine with a wide variety of properties. It has been used for many centuries as anthelmintic (Mc Donald et al, 2004;Tapondjou et al, 2002;Bostanian et al, 2005;Monzote et al, 2007;Quinlan et al, 2002;Kelzis et al, 2002).…”

Section: Introductionmentioning

confidence: 99%

Chemical composition and antimicrobial activity of crude, aqueous, ethanol extracts and essential oils ofDysphania ambrosioides(L.) Mosyakin & Clemants

Boutkhil

Idrissi

Amechrouq

et al. 2009

Acta Botanica Gallica

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Abstract.-Crude, aqueous, ethanol extracts and essential oils of aerial parts of Dysphania ambrosioides were investigated for their in vitro antimicrobial properties. The plant was collected from Agouray village near Meknès city of Morocco. D. ambrosioides is widely used as traditional folk medicine in Morocco. The main components in the oil were α-terpinene (61.04%), 4-carene (13.55%) and pcymene (12.94%). The antimicrobial activity was evaluated against 12 microorganisms using the disc-diffusion assay, well in agar method, minimal inhibition concentration (MIC) and minimal bactericidal concentration (MBC) values. The different extracts tested had no antimicrobial effect against the test microorganisms whereas the essential oil had inhibitory effects on the growth of bacteria, yeasts and fungi.

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Activity, toxicity and analysis of resistance of essential oil from Chenopodium ambrosioides after intraperitoneal, oral and intralesional administration in BALB/c mice infected with Leishmania amazonensis: A preliminary study

Cited by 47 publications

References 22 publications

Effect of Cinnamon Oil on icaA Expression and Biofilm Formation by Staphylococcus epidermidis

Effect of Cinnamon Oil on icaA Expression and Biofilm Formation by Staphylococcus epidermidis

Chemical composition and antiprotozoal activities of Colombian Lippia spp essential oils and their major components

Chemical composition and antimicrobial activity of crude, aqueous, ethanol extracts and essential oils ofDysphania ambrosioides(L.) Mosyakin & Clemants

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