Activity standardization, photon emission probabilities and half-life measurements of 177 Lu

Half-life measurement of the medical radioisotope 177Lu produced from the 176Yb(n,γ) reaction

“…The low activity of 177m Lu present in the solution was found to have no effect in determining the half-life of 177 Lu. Dryak et al [18], reported a detection limit of 6 × 10 −9 for 177m Lu when using 177 Lu n.c.a., confirming the results presented in this paper regarding the negligible amount of impurity present in solution for this method of production.…”

“…Of these only the measurement reported by Dryak et al [18] has used 177 Lu from production method 2) and therefore not required corrections for the 177m Lu impurity. In a recent evaluation, Kellett [20] identified that the presence of 177m Lu has had a significant influence on the half-life determinations, while Pommé et al [14] observed that the omission of the impurity subtraction led to a 0.5% error in their determined halflife after only 7.6 days in their measurement campaign.…”

“…There have been 14 previous publications reporting half-life measurements of 177 Lu [6][7][8][9][10][11][12][13][14][15][16][17][18][19], which are summarised in Table 1. Of these only the measurement reported by Dryak et al [18] has used 177 Lu from production method 2) and therefore not required corrections for the 177m Lu impurity.…”

Empirical decomposition and error propagation of medium-term instabilities in half-life determinations

“…With the enhanced rigor in experimental execution and data analysis, the metrological community is currently achieving better consistency at a higher level of accuracy than in the past. Examples of recently achieved convergence are the improved half-life values for 55 Fe [7,8], 109 Cd [9][10][11], 177 Lu [12][13][14][15][16], 209 Po [17][18][19], 225 Ac [20,21], 223 Ra [22,23], and 227 Th [24,25].…”