Activity of Matricaria chamomilla essential oil against anisakiasis

Activity of Tea Tree (Melaleuca alternifolia) Essential Oil against L3 Larvae ofAnisakis simplex

“…Romero et al [19] demonstrated that 125  μ g/mL of Matricaria chamomilla essential oil induced 100% larval mortality after 4 h in vitro and reduced the pathogenic effects in experimentally infected rats. The results obtained in our study show that TTO was effective, obtaining significant larvicidal effect at doses over 4  μ L/mL.…”

“…Otherwise, several plant essential oils and their derived compound have shown biocidal activity against Anisakis spp. [15–19]. …”

Natural products: Perspectives in the pharmacological treatment of gastrointestinal anisakiasis

“…Essential oil of Thymus vulgaris (T. vulgaris) was found to act on L3 larvae when added to the muscle tissue of the parasitized fish at a concentration of 10% in sunflower oil. In most cases, alterations were observed in the morphology of the larva, mainly involving the cuticle and the digestive tract, especially the ventricular area [23][24][25][26][27][28]. Essential oil of Piper nigrum (P. nigrum) killed 83.3% of parasites at 125 mg/mL while Myristica fragans (M. fragans) showed no activity (data not published).…”

“…Concentration [23] T. vulgaris 10% in oil sunflower 100.0 7 [28] M. chamomilla 125 mg/mL 100.0 4 [25][26][27] M. piperita concentrations of certain compounds found in Z. officinale and P. frutescens, such as [6]-shogaol (62.5 mg/mL), [6]-gingerol (250 mg/mL), perillaldehyde (125 mg/mL) and perillyl alcohol (250 mg/mL). Moreover, Lin et al [31] Suzuki et al [32] studied the effect of other compounds of natural origin.…”

“…The essential oils of M. piperita and M. chamomilla were studied in vivo by Romero et al [25][26][27], and it was observed that in rats treated with chamomile essential oil in conjunction with the larvae, only 2.2% had lesions in the gastric mucous membrane, as opposed to 93.3% in the control group. In rats treated with peppermint essential oil, no lesions appeared in the gastrointestinal tract, nor were there any larvae attached to the digestive tract, from which we can deduce that this essential oil significantly (P < 0.001) reduces the pathogenic capacity of the larvae when compared to the control.…”