Natural products: Perspectives in the pharmacological treatment of gastrointestinal anisakiasis

Valero, A.; Romero, María del Carmen Molina; Gómez-Mateos, Magdalena; Hierro, Ignacio; Navarro, M.

doi:10.1016/j.apjtm.2015.07.017

Cited by 15 publications

(31 citation statements)

References 29 publications

(33 reference statements)

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“…In vivo assays on larvae of A. simplex showed that LD 50 EOs ranged from 9.5 to 46.9 mg in a carrier of 0.5 mL of olive oil caused the dead of all larvae in the gastric cavity of rats (Valero et al, 2015). However, studies in vivo with EOs has been not performed with regard to larvae of Anisakis or other …”

Section: In Vitro Activity Of Essential Oils On Fish Parasitesmentioning

confidence: 99%

“…Many of these bioactive molecules are found at low concentrations (less than 1%), while a few of them are major compounds that can represent up to 70% of the total volume of oil and are mainly responsible for the bioactive effects of the EO (Bakkali et al, 2008;Cunha et al, 2017). Several of these secondary metabolites of medicinal plants present diverse antiparasitic activity (Bakkali et al, 2008;Soares and Tavares-Dias, 2013;Romero et al, 2014, Valero et al, 2015Hashimoto et al, 2016, Soares et al, 2016Sharifi-Rad et al, 2017).…”

Section: Secondary Metabolites Of Plants and Essential Oilsmentioning

confidence: 99%

“…The efficacy against different species of monogeneans has ranged from 60 to 100% (Tab. 2), and against nematodes from 0 to 100% (Valero et al, 2015). In this article, studies on in vitro use of EOs and their major compounds against Anisakis simplex published up to 2014 were not used, since there is an excellent review conducted recently by Valero et al (2015).…”

Section: In Vitro Activity Of Essential Oils On Fish Parasitesmentioning

confidence: 99%

“…2), and against nematodes from 0 to 100% (Valero et al, 2015). In this article, studies on in vitro use of EOs and their major compounds against Anisakis simplex published up to 2014 were not used, since there is an excellent review conducted recently by Valero et al (2015). These authors reviewed the in vitro efficacy of Cuminum cyminum, Cymbopogon citratus, Cymbopogon martinii, Cymbopogon winterianus, Litsea cubeba, Pelargonium graveolens, Origanum vulgare, Matricaria chamomilla, M. piperita, Myristica fragans and Piper nigrum on A. simplex, along with more than 30 major compounds.…”

Section: In Vitro Activity Of Essential Oils On Fish Parasitesmentioning

confidence: 99%

“…Most of the in vitro studies on the effects of EOs or their compounds have been directed to A. simplex (Valero et al, 2015), a nematode that can cause zoonosis in humans (Hierro et al, 2004;Romero et al, 2014;Giarratana et al, 2015;Valero et al, 2015;Pérez et al, 2016), along with monogeneans (Tab. 2), which are helminths ectoparasites that cause great economic losses in fish farming due to epizootics (Steverding et al, 2005;Soler-Jiménez et al, 2017).…”

Section: In Vitro Activity Of Essential Oils On Fish Parasitesmentioning

confidence: 99%

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Current knowledge on use of essential oils as alternative treatment against fish parasites

Tavares‐Dias¹

2018

Aquat. Living Resour.

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-This review article focuses on current knowledge about in vitro and in vivo experimentation relating to use of essential oils (EOs) to combat fish parasites. In addition, we discuss the existing methodologies used in studies to determine the antiparasitic activity of EOs, along with their toxicity and major compounds. The methodological approaches used to describe the anthelmintic properties of EOs were demonstrated. The consistency of their activity and thus their potential use for fish ectoparasites (in vitro and in vivo) and endoparasites (in vitro) control was reviewed. There is a clear need to find EOs and active agents of EOs to treatment in vivo against endoparasites of fish. Thus, progress may be achieved through considering the beneficial aspects of EOs when their complementarity and potentiality are exploited. EOs are therefore viable alternative sources of therapeutic products against fish parasites. On the other hand, use of chemotherapeutics has been increasingly questioned, such that constant environmental and consumer concerns regarding them now exist. The synergistic functions of EOs, in comparison with the action of one or two major compounds of these oils, seems unquestionable. It is possible that their activity is modulated by several molecules of the major compounds. Lastly, EOs are bioactive products that are viable sources of therapy against fish parasites. Although more than 3000 EOs are known, less than 0.4% of them have been tested on fish parasites. Thus, it has become clear that more studies testing these therapeutic alternatives are required, in order to evaluate the antiparasitic potential of other EOs for controlling fish parasites and to maximize their benefits to hosts.

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Section: In Vitro Activity Of Essential Oils On Fish Parasitesmentioning

confidence: 99%

Section: Secondary Metabolites Of Plants and Essential Oilsmentioning

confidence: 99%

Section: In Vitro Activity Of Essential Oils On Fish Parasitesmentioning

confidence: 99%

Section: In Vitro Activity Of Essential Oils On Fish Parasitesmentioning

confidence: 99%

Section: In Vitro Activity Of Essential Oils On Fish Parasitesmentioning

confidence: 99%

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Current knowledge on use of essential oils as alternative treatment against fish parasites

Tavares‐Dias¹

2018

Aquat. Living Resour.

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Use of Tunisian flavored olive oil as anisakicidal agent in industrial anchovy marinating process

et al. 2018

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Effectiveness of five flavored Tunisian olive oils on Anisakis larvae type 1: application of cinnamon and rosemary oil in industrial anchovy marinating process

et al. 2019

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BACKGROUND Anisakidosis is caused by the ingestion of raw or undercooked fish or cephalopods containing viable Anisakis larvae. Several natural extracts, oils, essential oils, and their compounds have been tested against Anisakis. In this study the effectiveness of Tunisian olive oil with different spices or plants (cardamom, cinnamon, ginger, laurel, and rosemary) was tested against Anisakis larvae type 1. RESULTS For the in vitro test, larvae were submerged separately in the oils mentioned above and observed to check viability. Cinnamon oil was the most effective against parasites with lethal time (LT) scores being LT50 = 1.5 days and LT100 = 3 days, followed by rosemary. Laurel, cardamom, and ginger oils were less effective. For the ex vivo experiment, cinnamon, and rosemary oils were tested in anchovy fillets, previously artificially parasitized. Cinnamon was the most effective against parasites (dead after 4 days) as compared to rosemary (7 days). CONCLUSION The use of cinnamon and rosemary‐flavored olive oil in the industrial marinating process can be considered as an efficient alternative to the freezing process required by European Regulation EC No 853/2004 to devitalize Anisakis. © 2019 Society of Chemical Industry

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Natural products: Perspectives in the pharmacological treatment of gastrointestinal anisakiasis

Abstract: This study shows that some natural products exhibited promising antianisakis properties.

Cited by 15 publications

References 29 publications

Current knowledge on use of essential oils as alternative treatment against fish parasites

Current knowledge on use of essential oils as alternative treatment against fish parasites

Use of Tunisian flavored olive oil as anisakicidal agent in industrial anchovy marinating process

Effectiveness of five flavored Tunisian olive oils on Anisakis larvae type 1: application of cinnamon and rosemary oil in industrial anchovy marinating process

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