Activity of Cephradine Against Anaerobes

Susceptibility of Gardnerella vaginalis to cephradine

“…Most authors now consider G. vaginalis to act synergistically with anaerobic bacteria in producing nonspecific vaginitis (9). Although several studies, including two from this laboratory, have shown cephradine to be active against anaerobic bacteria (1)(2)(3)12), few data exist on the susceptibility of G. vaginalis to cephradine (8,10) or the activity of the drug at pH's characteristic of infected vaginal secretions.…”