Activity against Microorganisms Affecting Cellulosic Objects of the Volatile Constituents of <i>Leonotis nepetaefolia</i> from Nicaragua

Casiglia, Simona; Bruno, Maurizio; Senatore, Felice

doi:10.1177/1934578x1400901127

Cited by 15 publications

(9 citation statements)

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“…The growing interest on natural products that can be used as an alternative to synthetic chemicals in order to prevent and reduce the dangerous effects of microorganisms on historical artifacts (Mansour, 2013;Rakotonirainy and Lave`drine, 2005;Stupar et al, 2014;Casiglia et al, 2014aCasiglia et al, , 2014bCasiglia et al, 2015) prompted us, in the frame of our previous reports on Sicilian Thymus ssp. (De Feo et al, 2003;De Martino et al, 2009), to investigate on the chemical composition and anti-microbial properties against several microorganism, including Bacillus subtilis, Fusarium oxysporum and Aspergillus niger, species infesting historical material (Kamel et al, 2014;Gupta, 2013), of T. capitatus, collected on the northern coast of Sicily at three different vegetative stages.…”

Section: Introductionmentioning

confidence: 99%

Influence of harvesting time on composition of the essential oil of Thymus capitatus (L.) Hoffmanns. & Link. growing wild in northern Sicily and its activity on microorganisms affecting historical art crafts

Casiglia

Bruno

Scandolera

et al. 2019

Arabian Journal of Chemistry

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One of the main factors affecting historical art crafts material is the biodeterioration performed by bacteria and fungi, in archives, museums or private collections. Several microorganisms cause degradation to the natural organic material such as fibers, woods, and dyes as well as to stone objects. These alterations produce deterioration of physical, chemical, mechanical and esthetic properties. Consequently, in this publication, we report the high antibacterial and antifungal activities of wild thyme essential oil, oil that can be used as an alternative natural tool in the fight against microorganisms affecting historical art crafts.Essential oil of the Thymus capitatus growing wild in northern Sicily has been extracted by hydrodistillation from aerial parts collected at different growth times. The constituents of the essential oil have been characterized by gas chromatography (GC) and GC-mass spectrometry.

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Section: Introductionmentioning

confidence: 99%

Influence of harvesting time on composition of the essential oil of Thymus capitatus (L.) Hoffmanns. & Link. growing wild in northern Sicily and its activity on microorganisms affecting historical art crafts

Casiglia

Bruno

Scandolera

et al. 2019

Arabian Journal of Chemistry

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“…Recently, also in the restore sector, the interest in biocompatible and eco-friendly solutions has increased. Many chemical products (quaternary ammonium compounds, chlorides, hypochlorites, and so on) are not used anymore and, when possible, a “green solution” is preferred [44,46,47,48,49,50]. There are less publications and application of natural eco-biocide for the stone artworks, but if these artefacts are outdoor, they are more steadily and repeatedly attacked by biodeteriogens [45,51,52].…”

Section: Introductionmentioning

confidence: 99%

The Essential Oil of Thymbra capitata and its Application as A Biocide on Stone and Derived Surfaces

Candela

Maggi

Lazzara

et al. 2019

Plants

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Many chemicals used nowadays for the preservation of cultural heritage pose a risk to both human health and the environment. Thus, it is desirable to find new and eco-friendly biocides that can replace the synthetic ones. In this regard, plant essential oils represent effective alternatives to synthetic substances for the preservation of historical monuments. Thymbra capitata (syn. Thymus capitatus) is a medicinal and aromatic plant growing in the Mediterranean area and endowed with important pharmacological properties related to its essential oil. Among them, the antimicrobial ones make the T. capitata essential oil an ideal candidate for industrial applications; for instance, as biocide for the inhibition and elimination of biological patinas of cyanobacteria and green algae on historical monuments. In the present work, we studied the chemical composition of the essential oil from T. capitata growing in Malta by gas chromatography-mass spectrometry (GC/MS). The major volatile component is the phenolic monoterpene carvacrol (73.2%), which is capable of damaging the cytoplasmic membrane and to interfere both in the growth curve and in the invasive capacity, though the contribution of minor components γ-terpinene and p-cymene cannot be disregarded. For the oil application on the stone surface, Pickering emulsions systems were prepared with an essential oil/water 1:3 mass ratio stabilized with kaolinite at 4 mass% in the presence of Laponite®; this allowed to limit the fast volatility of the oil and guaranteed a better application and an easier removal from the artefacts attacked by biodeteriogens both indoor and outdoor. This formulation caused the elimination of biodeteriogens from treated surfaces without residuals or films on artworks surface, and the effect was retained up to four months.

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“…Furthermore, lupeol isolated from Lonchocarpus araripensis attenuated allergic airway inflammation in mice . The phytol, a diterpenoid, was identified as the most abundant compound in essential oil obtained from the aerial parts of Cleome rutidosperma , Leonotis nepetaefolia and Cleome serrata and exhibited antimicrobial activity. The phytol extracted from Justicia gendarussa has shown potent anti‐inflammatory activity by inhibiting histamine, bradykinin and prostaglandin when compared to standard diclofenac in a rat paw edema model .…”

Section: Discussionmentioning

confidence: 99%

Inhibitory Effect of Supercritical Extracts from Arctium lappa L. on the Lectin Pathway of the Complement System

Bavia

Fontana

Bovo

et al. 2019

Chemistry & Biodiversity

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The complement system participates in host defense by eliminating microorganisms and triggering inflammation. However, insufficient control or exacerbated complement activation contributes to inflammatory diseases. Since promising antioxidant and anti-inflammatory activities have been identified in Arctium lappa L. extracts, this study aims to explore the effect of A. lappa extracts on the lectin pathway (LP) of complement activation. Four extracts were obtained by supercritical extraction using scCO 2 with or without ethanol as cosolvent, at different temperatures and pressures (E1: 2.2 mg/mL, E2: 2.6 mg/mL and E3: 2.0 mg/mL, E4: 1.5 mg/ mL). To evaluate the effect of A. lappa extracts on the LP activation, an ELISA assay using mannose binding lectin pathway of complement was carried out with C4 detection. All extracts showed a concentration-dependent inhibitory effect on the activation of complement by the LP. The following IC 50 were observed for E1, E2, E3 and E4: 179.4 μg/mL, 74.69 μg/mL, 119.1 μg/mL and 72.19 μg/mL, respectively. Our results suggest that A. lappa extracts are potential candidates for the treatment of inflammatory disorders that are complement-related. ResultsThe A. lappa extracts E1, E2, E3 and E4 displayed an inhibitory effect on the functional activity of lectin pathway (Figure 1). The extract E1 (at concentration Figure 1. Effect of Arctium lappa L. extracts on functional activity of the MBL lectin pathway of complement system. The activation of the lectin pathway was evaluated in the presence of four extracts obtained under different conditions: The extracts E1 and E2 were obtained using scCO 2 in the presence (A) and absence of ethanol (B) as co-solvent, respectively, at 200 bar and 60°C. The extract E3 was obtained using scCO 2 + ethanol at 150 bar and 80°C (C). The extract E4 was obtained using scCO 2 + ethanol at 250 bar and 80°C (D). The final concentration of all extracts evaluated is represented in the x axis. All extracts dilutions were compared with the positive control (NHS diluted to represent 50 % of lectin pathway activation) by one-way ANOVA and Bonferroni's multiple comparison test (***p < 0.001, **p < 0.01, and *p < 0.05). All biological experiments were performed twice in duplicate and the results were expressed as mean and standard deviation.

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Activity against Microorganisms Affecting Cellulosic Objects of the Volatile Constituents of Leonotis nepetaefolia from Nicaragua

Cited by 15 publications

References 1 publication

Influence of harvesting time on composition of the essential oil of Thymus capitatus (L.) Hoffmanns. & Link. growing wild in northern Sicily and its activity on microorganisms affecting historical art crafts

Influence of harvesting time on composition of the essential oil of Thymus capitatus (L.) Hoffmanns. & Link. growing wild in northern Sicily and its activity on microorganisms affecting historical art crafts

The Essential Oil of Thymbra capitata and its Application as A Biocide on Stone and Derived Surfaces

Inhibitory Effect of Supercritical Extracts from Arctium lappa L. on the Lectin Pathway of the Complement System

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