Actividad antidiabética

Books, OmniaScience; Rivas-Morales, Catalina; Oranday-Cárdenas, María Azucena; Verde-Star, María Julia; González, Sergio García; Leos-Rivas, Catalina; García-Hernández, David Gilberto; Sánchez‐García, Eduardo; Castillo, Sandra; García-Palencia, Patricia; Moreno-Peña, D.P.; Cordero-Pérez, Paula; Pérez-Hernández, Raymundo Alejandro; Ramos-Ibarra, María Luisa; Torres-González, Liliana; Cienfuegos-Pecina, Eduardo; Ortíz-Martínez, David-Mizael; Martínez‐Torres, Ana Carolina; Uscanga‐Palomeque, Ashanti Concepción; Rodríguez‐Padilla, Cristina; Cabello-Ruiz, Ethel Daniela; Núñez-González, María Adriana; Cruz, Víctor Manuel Torres de la; Morales-Rubio, María Eufemia; Espinosa-Leal, Claudia; Garza-Padrón, Ruth Amelia; Armendáriz-Barragán, Brenda; Álvarez-Román, Rocío; Galindo-Rodríguez, Sergio Arturo

doi:10.3926/oms.342

Cited by 1 publication

(1 citation statement)

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“…After 4 h, a second glucose measurement was made. These doses were determined based on a review of the antidiabetic activity of plants made by our group, in which reported doses oscillated between 200 and 500 mg/kg [27].…”

Section: Methodsmentioning

confidence: 99%

Hypoglycemic Activity ofTilia americana,Borago officinalis,Chenopodium nuttalliae, andPiper sanctumon Wistar Rats

Rodríguez-Magaña

Cordero-Pérez

Rivas-Morales

et al. 2019

Journal of Diabetes Research

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Diabetes mellitus (DM) is considered the epidemic of the 21st century. Traditional medicine uses plants to treat DM; many of these have hypoglycemic effects in both animal models and diabetic patients. Our objective was to evaluate the hypoglycemic activity of Tilia americana, Borago officinalis, Chenopodium nuttalliae, and Piper sanctum on diabetic rats. The methanolic extracts of the plants under study were obtained by Soxhlet extraction. Toxicity was evaluated on Artemia salina; the antioxidant potential was evaluated using the DPPH technique. Hypoglycemic capacity at doses of 250 and 500 mg/kg was tested on Wistar rats with diabetes induced by alloxan (120 mg/kg). The toxicity on A. salina was null for the extracts of B. officinalis and P. sanctum, moderate for T. americana, and highly toxic for C. nuttalliae. The relevant extract of T. americana var. mexicana showed antioxidant activity. Three plants of the studied plants showed hypoglycemic activity: Tilia Americana (p=0.0142), Borago officinalis (p=0.0112), and Piper sanctum (p=0.0078); P. sanctum was the one that showed the greatest reduction in glucose levels at a lower dose.

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Section: Methodsmentioning

confidence: 99%