Active stone removal is a safe option for ocotogenarians and nonagenarians with nephrolithiasis

Eredics, Klaus; Drerup, Martin; Özsoy, Mehmet; Wehrberger, Clemens; Lenz, Matthias; Ramesmayer, Christian; Stolzlechner, Philipp; Zanier, Johannes; Falkensammer, Claudia E.; Handjiev, Ivan; Wasserscheid, Andreas; Seklehner, Stephan

doi:10.1007/s00345-023-04304-3

Cited by 5 publications

(11 citation statements)

References 24 publications

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“…In conclusion, all studies showed that PCNL is safe, effective, and practically applicable—especially for older patients [59 ▪▪ ,66]. Overall, age without comorbidities should not be considered a decisive factor for the likelihood of effectiveness and complications [59 ▪▪ ].…”

Section: Operative Treatmentmentioning

confidence: 83%

“…In conclusion, all studies showed that URS is safe, effective, and applicable, particularly for older patients [59 ▪▪ ,66]. Most studies reported similar complication rates and SFR [59 ▪▪ ,66], while Beradinelli et al [63] further concluded that age without comorbidities should not be considered a predictive factor for the likelihood of complications.…”

Section: Operative Treatmentmentioning

confidence: 87%

“…In the context of elderly patients, all studies underscored the effectiveness and safety of ESWL, noting no statistically significant differences in complications and SFR [66,87–90]. However, while the three-month success rate in the general population remains comparable to URS and PCNL [91] in the geriatric population, it is notably lower [92].…”

Section: Operative Treatmentmentioning

confidence: 99%

“…Due to its higher stone free rate (SFR) coupled with a lower likelihood of complications compared to PCNL, URS is now considered the first-line therapy, especially for elderly patients, even for stones exceeding 20 ] compared findings from six mostly retrospective studies that defined the elderly group differently (range: !60 to !85 years) [60][61][62][63][64][65]. Additionally, insights from a recent retrospective study by Eredics et al [66] comparing outcomes of the three commonly employed surgical approaches adds important context to the changing field of urolithiasis care.…”

Section: Andandmentioning

confidence: 99%

“…A recent review by Schulz et al [59 ▪▪ ] compared findings from six mostly retrospective studies that defined the elderly group differently (range: ≥60 to ≥85 years) [60–65]. Additionally, insights from a recent retrospective study by Eredics et al [66] comparing outcomes of the three commonly employed surgical approaches adds important context to the changing field of urolithiasis care.…”

Section: Operative Treatmentmentioning

confidence: 99%

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Prevention, diagnosis, and treatment of urolithiasis in geriatric patients - differences, similarities and caveats in comparison to the general population

Schrag,

Diarra,

Veser

2024

Current Opinion in Urology

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Purpose of the review Purpose of the review is to address management and prevention of urolithiasis in elderly patients examining the dynamic interplay between general measures, dietary adjustments, lifestyle modifications, and targeted pharmacological and/ or surgical interventions. The goal is to provide understanding of the evolving strategies required for effective urolithiasis prevention in the geriatric population. Recent findings Age-specific diagnostic considerations are necessary because urolithiasis in the elderly population is characterized by bigger stones, greater peri-operative risks, and heightened symptom severity. When comorbidities are present, conservative treatments – especially analgesia – provide difficulties. Surgical procedures prove to be safe and effective, with complication rates and practical application comparable to younger cohorts. Prevention approaches that include lifestyle changes and the investigation of novel pharmaceutical options such as sodium-dependent glucose co-transporter 2 (SGLT-2)-inhibitors are promising in the management of urolithiasis in the elderly population. Summary Our review offers a thorough investigation of urolithiasis in the elderly population, elucidating distinct clinical manifestations, complex diagnostic issues, and treatment implications. The safety and effectiveness of ureteroscopy in older patients, as well as the possible prophylactic function of SGLT-2-I, offer crucial insights for clinicians. Subsequent studies are necessary to enhance age-specific therapies, addressing the distinct obstacles presented by urolithiasis in the elderly population within this rapidly growing demographic.

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Section: Operative Treatmentmentioning

confidence: 83%