Active and passive immunization against Pseudomonas aeruginosa infection of burned patients

Roe, Elizabeth; Jones, Rhys

doi:10.1016/0305-4179(83)90108-0

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1991

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Cited by 8 publications

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“…Pseudomonas aeruginosa is a common clinical isolate (1,3,5,(20)(21)(22)25). The progress from colonization to infection is usually accompanied by an increase of serum antibody titers to the main virulence factors of this microorganism-such as lipopolysaccharide (LPS) and exotoxin A (ExA) (6,22).…”

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confidence: 99%

Characterization of Antibody Response to Pseudomonas aeruginosa in Patients with Wound Infections

Trafny

Grzybowski

Patzer

et al. 1991

Microbiology and Immunology

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ELISA was used to measure the amount and avidity of IgG antibodies to exotoxin A (ExA) and 7 Fisher's immunotypes of lipopolysaccharide (LPS) in the sera of 13 patients with mild or moderate Pseudomonas aeruginosa infections.Changes in the specificity of tested sera during the course of infection were demonstrated. A statistically significant increase was seen in the amount and avidity of the antibodies to ExA in a majority of the sera, and an increase was seen in amount of antibodies to LPS immunotype 4 in the sera of patients with moderate infections.

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confidence: 99%