Characterization of Antibody Response to <i>Pseudomonas aeruginosa</i> in Patients with Wound Infections

Trafny, Elżbieta Anna; Grzybowski, Jacek; Patzer, Jan; Popiel, D; Wrembel-Wargocka, Jolanta; Dzierżanowska, D; Zawistowska-Marciniak, Irena; Kobus, Kazimierz

doi:10.1111/j.1348-0421.1991.tb01574.x

Cited by 4 publications

(1 citation statement)

References 24 publications

(15 reference statements)

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“…P. aeru is an opportunistic pathogen associated with wound infections (Trafny et al, 1991) and urinary tract infections. When cultured in vitro, P. aeru biofilm was formed (Feng et al, 2000).…”

Section: Introductionmentioning

confidence: 99%

Detection of Pseudomonas aeruginosa using a wireless magnetoelastic sensing device

Pang

Huang

Cai

et al. 2007

Biosensors and Bioelectronics

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Section: Introductionmentioning

confidence: 99%

Detection of Pseudomonas aeruginosa using a wireless magnetoelastic sensing device

Pang

Huang

Cai

et al. 2007

Biosensors and Bioelectronics

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Amount and avidity of IgG antibodies toPseudomonas aeruginosa exotoxin A antigen in cystic fibrosis patients

Polanec

Patzer

Grzybowski

et al. 1997

Pathol. Oncol. Res.

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Amount and avidity of serum IgG antibodies to Pseudomonas aeruginosa exotoxin A in sera of 31 patients with cystic fibrosis (CF) was studied. Eight patients had P. aeruginosa isolated from the sputum on multiple occasions, while from 23 patients no P. aeruginosa was isolated. Amount of IgG antibodies to P. aeruginosa exotoxin A were significantly increased in the serum of patients with P. aeruginosa pulmonary colonization (p<0.0001). On the contrary, serum IgG avidity in the colonized and in the non-colonized CF patients was low (<10) and was statistically different when compared to the 30 age-matched healthy controls (p<0.0001). There was no change in IgG avidity in six chronically infected CF patients from whom we obtained serum samples after half a year period (p=0,55).

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Detection of Pseudomonas aeruginosa in patients with cystic fibrosis

Tramper-Stranders

Ent

Wolfs

2005

Journal of Cystic Fibrosis

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Chronic pulmonary colonisation with Pseudomonas aeruginosa (PA) in patients with CF is associated with a high morbidity and mortality. Adequate treatment of first acquisition of PA might prevent or postpone chronic colonisation. Early detection of PA is therefore of major importance. Currently, cultures of oropharynx or sputum are most commonly practised. However, oropharyngeal culture has limitations both in the positive and negative predictive value for the presence of PA in the lower respiratory tract. Induction of sputum has little benefit in detection of PA. Serology might have additional value in early detection, when bacterial density is too low to be detected by culture. Molecular techniques are not yet widespread used for detection of PA, but have in general a high sensitivity. In this review, we describe the value of different diagnostic techniques for detecting PA.

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Characterization of Antibody Response to Pseudomonas aeruginosa in Patients with Wound Infections

Cited by 4 publications

References 24 publications

Detection of Pseudomonas aeruginosa using a wireless magnetoelastic sensing device

Detection of Pseudomonas aeruginosa using a wireless magnetoelastic sensing device

Amount and avidity of IgG antibodies toPseudomonas aeruginosa exotoxin A antigen in cystic fibrosis patients

Detection of Pseudomonas aeruginosa in patients with cystic fibrosis

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