Active abdominal bleeding: contrast-enhanced sonography

Catalano, Orlando; Cusati, Bianca; Nunziata, Antonio; Siani, Alfredo

doi:10.1007/s00261-005-0369-6

Cited by 89 publications

(61 citation statements)

References 31 publications

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“…Less data are available on IV CE-US in children. The results of the few reports are similar to those from adults, and prove the high diagnostic potential of US-CAs in reducing the need for radiation-burdened imaging, particularly also in investigations of moderate blunt abdominal trauma [78][79][80][81][82].…”

Section: Discussionsupporting

confidence: 65%

Application of a second-generation US contrast agent in infants and children—a European questionnaire-based survey

Riccabona

2012

Pediatr Radiol

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Background No US contrast agent (US-CA) is currently licensed for use in children.Objective To survey the off-label use in children of a second-generation US-CA. Materials and methods Questionnaires were e-mailed to European paediatric radiologists, who were asked about their experience with the second-generation US-CA Sonovue® (Bracco, Milan, Italy). Number of examinations per indication and adverse effects were recorded. Examinations were categorised by intravenous or intracavitary use of US-CA. Results Out of 146 respondents, 88 stated that they did not perform contrast-enhanced US in children, but 36 of these (44%) would appreciate paediatric approval. Fortyfive centres reported 5,079 examinations in children (age mean: 2.9 years; range: birth-18 years, M/F: 1/ 2.8). The majority (4,131 [81%] in 29 centres) were intravesical applications. The minority (948 [19%] in 30 centres) were intravenous applications. No adverse effects had been recorded from intravesical use. Six minor adverse effects (skin reaction, unusual taste, hyperventilation) had been recorded after five intravenous studies (0.52%). Conclusion Responses suggest a favourable safety profile of this second-generation US-CA in children. It also demonstrates a demand for such US-CA from paediatric radiologists.

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Section: Discussionsupporting

confidence: 65%

Application of a second-generation US contrast agent in infants and children—a European questionnaire-based survey

Riccabona

2012

Pediatr Radiol

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“…Because the ability to detect the blood flow on CDUS is dependent on the flow velocity, detecting bleeding with a low flow velocity is difficult. Contrast-enhanced ultrasound (CEUS) exhibits 100% sensitivity and 100% specificity for active bleeding and is useful for detecting less dramatic or non-arterial bleeding (13,14). However, no reports have investigated the rate of detection of microbubble flow signals along the needle tract following percutaneous liver biopsy.…”

Section: Introductionmentioning

confidence: 99%

Assessment of Track Microbubble Flow Signals on Contrast-enhanced Ultrasound with Perflubutane Following Percutaneous Liver Biopsy

et al. 2013

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Objective It is important to detect post-liver biopsy hemorrhage early and confirm hemostasis in the clinical setting. Contrast-enhanced ultrasound (CEUS) is a sensitive and highly specific tool for detecting active bleeding. The aim of this study was to investigate the rate of detection of track microbubble flow signals on CEUS with perflubutane following liver biopsy and to assess the disappearance of these signals.Methods Microbubble flow signals along the needle track on CEUS were examined in 100 patients who underwent percutaneous US-guided liver biopsies. The microbubble flow signals were examined repeatedly until their disappearance. The patients were followed up with clinical and laboratory data to detect clinically significant hemorrhaging. Results Microbubble flow signals on CEUS following percutaneous liver biopsy were seen in 33% of the patients. There were no significant differences in the platelet count, prothrombin time or length of the biopsy specimen between the patients with and those without microbubble flow signals on CEUS. The microbubble flow signals disappeared over time in all patients. There were no cases of clinically significant hemorrhaging in the present study. Conclusion Track microbubble flow signals on CEUS are frequently observed after biopsies. The disappearance of a microbubble flow signal is a useful index for confirming hemostasis of postbiopsy hemorrhaging.

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“…In 1/3 of our patients the additional information provided by the contrast-enhanced examination (classified as highly relevant in 10% and moderately relevant in 17.5%) substantially altered case management by furnishing better documentation/staging of the traumatic lesions and by excluding the traumatic nature of lesions observed on the baseline study. Another advantage of CEUS (compared with US) is that it can detect ongoing hemorrhages [20,33]. The use of CEUS to study scrotal disorders has been limited thus far, but evidence seems to be emerging [18,20] that one of its most interesting applications may be in the work-up of the acute scrotum, including both traumatic (as demonstrated by the present report) and nontraumatic lesions.…”

Section: Discussionmentioning

confidence: 80%

Contrast-enhanced sonography in blunt scrotal trauma

Lobianco

Regine

Siero

et al. 2011

Journal of Ultrasound

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The scope of this study was to determine whether contrast-enhanced ultrasonography (CEUS), compared with basic US, can increase diagnostic confidence and provide relevant information on blunt scrotal trauma. Over a period of 75 months we examined 40 patients seen consecutively for blunt scrotal trauma using high-resolution US, color-power Doppler, low mechanical index CEUS, and power Doppler after IV administration of contrast medium (SonoVue Ò ). In the 24 cases that were positive, concordance between basal US and CEUS findings was grade 0 (absent) in 4 cases, grade 1 (low) in 3, grade 2 (moderate) in 8, and grade 3 (high) in 9. The relevance of the additional information provided by CEUS was classified as follows: high in 4/40 (10%), moderate 7/40 (17,5%), low 13/40 (32,5%), none in 14/40 (35%). Our findings demonstrate that CEUS is appreciably more sensitive in detecting damage caused by blunt scrotal trauma, particularly small lesions. It is also useful for differential diagnosis and marginalization of corpuscular fluid collections, fractures, and above all ruptures, which require immediate surgery. In our series 2 out of 3 (67%) patients with testicular rupture were diagnosed only by CEUS. We feel that the use of CEUS can significantly improve diagnostic confidence in cases of closed scrotal trauma although these conclusions need to be confirmed in larger case series.Sommario Scopo del nostro lavoro è stato di valutare l'eventuale maggiore confidenza diagnostica e contenuto informativo dell'ecografia con mezzo di contrasto e.v. (CEUS) nel trauma scrotale chiuso rispetto all'indagine ecografica (US) di base. Nell'arco di 75 mesi abbiamo esaminato 40 pazienti consecutivi con trauma scrotale chiuso, utilizzando US ad alta risoluzione, color-power-Doppler basale, ecocontrastografia a basso indice meccanico, power Doppler dopo mdc e.v. Il mdc usato è stato il SonoVue Ò . Nei 24 casi positivi, la concordanza tra US basale e CEUS è stata di grado 0 (assente) in 4 casi, di grado 1 (bassa) in 3, di grado 2 (medio) in 8, di grado 3 (elevato) in 9. La rilevanza del contenuto informativo aggiuntivo della * Award for the best oral presentation at the XXII SIUMB National Congress.* Corresponding author. Radiology Department, Santa Maria delle Grazie Hospital, Pozzuoli, Naples, Italy. E-mail address: robertolobianco@virgilio.it (R. Lobianco).Available online at www.sciencedirect.com CEUS veniva ritenuta: elevata in 4/40 (10%), media 7/40 (17,5%), bassa 13/40 (32,5%), assente in 14/40 (35%). I nostri risultati mostrano che la CEUS migliora sensibilmente la detezione dei segni di trauma rispetto l'US basale, specialmente nelle piccole lesioni. Essa è inoltre importante nella diagnosi differenziale e marginalizzazione delle raccolte fluide corpuscolate, nelle fratture e, di grande evidenza, nelle rotture, che impongono l'immediato intervento chirurgico: nella nostra casistica 2 casi su 3 di rotture (67%) si sono resi evidenti soltanto alla CEUS. Riteniamo che l'uso della CEUS possa aumentare significativamente la co...

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Active abdominal bleeding: contrast-enhanced sonography

Cited by 89 publications

References 31 publications

Application of a second-generation US contrast agent in infants and children—a European questionnaire-based survey

Application of a second-generation US contrast agent in infants and children—a European questionnaire-based survey

Assessment of Track Microbubble Flow Signals on Contrast-enhanced Ultrasound with Perflubutane Following Percutaneous Liver Biopsy

Contrast-enhanced sonography in blunt scrotal trauma

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