Activation of the Ethylene Gas Response Pathway in Arabidopsis by the Nuclear Protein ETHYLENE-INSENSITIVE3 and Related Proteins

Chao, Qimin; Rothenberg, Madge; Solano, Roberto; Roman, Gregg; Terzaghi, William; Ecker, Joseph R.

doi:10.1016/s0092-8674(00)80300-1

Cited by 900 publications

(876 citation statements)

References 55 publications

Supporting

Mentioning

843

Contrasting

Unclassified

Order By: Relevance

“…The ethylene signal is transduced to ETHYLENE INSEN-SITIVE3 (EIN3) through CONSTITUTIVE TRIPLE RE-SPONSE1 (CTR1) (Kieber et al 1993) and ETHYLENE INSENSITIVE2 (EIN2) (Alonso et al 1999). EIN3 is a transcription factor that plays a crucial role in regulation of expression of ethylene responsive genes (Chao et al 1997;Solano et al 1998). Studies have also revealed that in absence of ethylene EIN3 protein is quickly degraded through a ubiquitin-proteasome pathway mediated by two F-box proteins, [EIN3-binding F box protein 1 and 2 (EBF1 and EBF2)] whereas EIN3 protein is stabilized by ethylene itself (Guo and Ecker 2003;Potuschak et al 2003;Gagne et al 2004).…”

Section: Role Of Ethylene In Regulation Of Fruit Ripeningmentioning

confidence: 99%

The fading distinctions between classical patterns of ripening in climacteric and non-climacteric fruit and the ubiquity of ethylene—An overview

2011

View full text Add to dashboard Cite

The process of fruit ripening is normally viewed distinctly in climacteric and non-climacteric fruits. But, many fruits such as guava, melon, Japanese plum, Asian pear and pepper show climacteric as well as non-climacteric behaviour depending on the cultivar or genotype. Investigations on in planta levels of CO 2 and ethylene at various stages of fruits during ripening supported the role and involvement of changes in the rate of respiration and ethylene production in non-climacteric fruits such as strawberry, grapes and citrus. Non-climacteric fruits are also reported to respond to the exogenous application of ethylene. Comparative analysis of plant-attached and plant-detached fruits did not show similarity in their ripening behaviour. This disparity is being explained in view of 1. Hypothetical ripening inhibitor, 2. Differences in the production, release and endogenous levels of ethylene, 3. Sensitivity of fruits towards ethylene and 4. Variations in the gaseous microenvironment among fruits and their varieties. Detailed studies on genetic and inheritance patterns along with the application of '-omics' research indicated that ethylene-dependent and ethylene-independent pathways coexist in both climacteric and non-climacteric fruits. Auxin levels also interact with ethylene in regulating ripening. These findings therefore reveal that the classification of fruits based on climacteric rise and/or ethylene production status is not very distinct or perfect. However, presence of a characteristic rise in CO 2 levels and a burst in ethylene production in some non-climacteric fruits as well as the presence of system 2 of ethylene production point to a ubiquitous role for ethylene in fruit ripening.

show abstract

Section: Role Of Ethylene In Regulation Of Fruit Ripeningmentioning

confidence: 99%

The fading distinctions between classical patterns of ripening in climacteric and non-climacteric fruit and the ubiquity of ethylene—An overview

2011

View full text Add to dashboard Cite

show abstract

“…EIN2 was reported to localize at the ER membrane when transiently expressed in tobacco leaf cells [4]. EIN3 (ETHYLENE INSENSITIVE3) and its homolog EIL1 (EIN3-LIKE1) are two nuclear-localized transcription factors genetically acting downstream of EIN2 [5,6]. However, it remains a long mystery on how the ethylene signal is transmitted from ER-located EIN2 into the nucleus to modulate EIN3/EIL1-directed transcription.…”

mentioning

confidence: 99%

Activation of ethylene signaling is mediated by nuclear translocation of the cleaved EIN2 carboxyl terminus

et al. 2012

View full text Add to dashboard Cite

“…We hypothesized that HOS1 is associated with ethylene signaling, because the hos1-3 mutant showed similar phenotypes in leaf expansion to the ctr1 mutant that exhibits constitutive ethylene responses. 14 To investigate whether alterations in ethylene signaling underlie reduced leaf expansion of hos1-3, we employed a chemical inhibitor of ethylene receptors, STS. The ethylene receptors require the copper ion for high-affinity ethylene binding.…”

mentioning

confidence: 99%

The E3 ubiquitin ligase HOS1 is involved in ethylene regulation of leaf expansion inArabidopsis

Lee

Seo

2015

Plant Signaling & Behavior

View full text Add to dashboard Cite

Ethylene regulates a variety of physiological processes, such as flowering, senescence, abscission, and fruit ripening. In particular, leaf expansion is also controlled by ethylene in Arabidopsis. Exogenous treatment with ethylene inhibits leaf expansion, and consistently, ethylene insensitive mutants show increased leaf area. Here, we report that the RING finger-containing E3 ubiquitin ligase HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES 1 (HOS1) regulates leaf expansion in an ethylene signaling pathway. The HOS1-deficient mutant showed reduced leaf area and was insensitive to ethylene perception inhibitor, silver thiosulfate (STS). Accordingly, genes encoding ethylene signaling components were significantly up-regulated in hos1-3. This study demonstrates that the HOS1 protein is involved in ethylene signal transduction for the proper regulation of leaf expansion possibly under environmentally stressful conditions.Leaf expansion is a crucial process that not only determines the shape and size of mature leaves but also ensures its photosynthetic capacity for plant growth and development. 1,2 It is influenced by multiplicity of environmental factors, such as water availability and day length. 3,4 In addition, endogenous hormone signaling is also intensively involved in the control of leaf expansion. Promotive roles of auxin, brassinosteroid, and gibberellin in leaf expansion have been demonstrated. [5][6][7] The simple hydrocarbon ethylene is a gaseous plant hormone that regulates a variety of developmental processes, such as seed germination, cell elongation, abscission, senescence, sex determination, and fruit ripening. [8][9][10][11][12][13] It has been also proposed that ethylene negatively regulates leaf expansion process. Exogenous ethylene treatment results in reduced leaf area. 14 Furthermore, ethylene insensitive mutants, such as ethylene receptor 1 (etr1) and ethylene response sensor 1 (ers1), show increased leaf size. 15,16 Five receptor isoforms are responsible for ethylene perception: ETR1, ETR2, ERS1, ERS2, and ETHYLENE INSENSITIVE 4 (EIN4). 17 Their ethylene perception is integrated into a negative regulator of ethylene signaling, CONSTITUTIVE TRIPLE RESPONSE 1 (CTR1) Ser/Thr protein kinase, 18 which in turn regulates a series of transcriptional cascades in order to control ethylene-dependent physiological processes. EIN2 is a representative positive signaling regulator and subsequently activates genes encoding EIN3 and related EIN3-LIKE (EIL), which further regulate expression of ETHYLENE-RESPONSE FACTORs (ERFs). 19,20 In the presence of ethylene, ethylene receptors inactivate kinase activity of CTR1 so that subsequent transcriptional cascades are activated. 21 Although ethylene signaling pathways have been intensively investigated, its intricate networks with other signaling pathways remain to be unraveled.The RING-type E3 ligase HOS1 was originally reported as cold signaling attenuator. 22 The cold-activated HOS1 protein executes protein turnover of the INDUCER OF CBF EXPRESSION1 (ICE1) MYC-l...

show abstract

Activation of the Ethylene Gas Response Pathway in Arabidopsis by the Nuclear Protein ETHYLENE-INSENSITIVE3 and Related Proteins

Cited by 900 publications

References 55 publications

The fading distinctions between classical patterns of ripening in climacteric and non-climacteric fruit and the ubiquity of ethylene—An overview

The fading distinctions between classical patterns of ripening in climacteric and non-climacteric fruit and the ubiquity of ethylene—An overview

Activation of ethylene signaling is mediated by nuclear translocation of the cleaved EIN2 carboxyl terminus

The E3 ubiquitin ligase HOS1 is involved in ethylene regulation of leaf expansion inArabidopsis

Contact Info

Product

Resources

About