Activation of human polymorphonuclear neutrophil functions by interferon-gamma and tumor necrosis factors

Blocking tumor necrosis factor paved the way for targeted therapeutics in inflammatory diseases

“…However, this was short-lived. The name change for TNF was protested as inappropriate since TNF and LT share only 28% similarity at protein level [9] . In 1993, a second member of LT family was discovered and named LTβ, and the prototype LT was referred to as LTα [10] .…”