1980
DOI: 10.1055/s-2008-1074985
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Actions Neuromusculaire et Cardiaque d'un Extrait Alcaloïdique de Strychnos icaja

Abstract: Strychnos icaja BAILL is a well-known tetanizing poison, containing strychnine and 12-hydroxy-derivative arnongst rnany other tertiary alkaloids. We have studied quaternary alkaloids of S. icaja root Adresse: Service de Pharmacognosie

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“…Kambu et al have shown that it may be possible to prepare alkaloid extracts that have either predominantly convulsant (strychnine-like) or muscle-relaxant properties. 1011 The authors have shown that the quaternary alkaloidal fraction, which is more water soluble than the tertiary alkaloidal fraction, has a pronounced muscle relaxant activity and strong cardiotonic action, with negative chronotropic and inotropic effects ending in irreversible cardiac arrest. S.…”
Section: Family -Annonaceaementioning
confidence: 99%
“…Kambu et al have shown that it may be possible to prepare alkaloid extracts that have either predominantly convulsant (strychnine-like) or muscle-relaxant properties. 1011 The authors have shown that the quaternary alkaloidal fraction, which is more water soluble than the tertiary alkaloidal fraction, has a pronounced muscle relaxant activity and strong cardiotonic action, with negative chronotropic and inotropic effects ending in irreversible cardiac arrest. S.…”
Section: Family -Annonaceaementioning
confidence: 99%