Acrolein and Methacrolein

Abstract

The article contains sections titled: 1. Introduction 2. Properties 2.1. Physical Properties 2.2. Chemical Properties 3. Production 3.1. Acrolein by Propene Oxidation 3.2. Methacrolein 4. Quality and Analysis 5. Handling, Storage, and Transportation 6. Uses and Production Data 7. Toxicology and Ecotoxicology 7.1. Toxicology 7.2. Ecotoxicology Acrolein is the simplest unsaturated aldehyde. It is an important intermediate in the production processes of a variety of substances. The main use of isolated acrolein is in the production of d,l ‐methionin, but in far more production processes, acrolein is used without purification. Acrolein is an extremely reactive chemical and, in very low concentrations, acts as a very effective broad‐spectrum biocide. Methacrolein is produced commercially as an organic intermediate, which is used as building block for chain expansions or, in limited application, in the synthesis of flavors and fragrances.

Aerobic Copper-Catalyzed Organic Reactions

“…66 Studies of copper oxides in a flow reactor for this transformation indicate competing combustion, particularly when the catalyst was oxidized before use. 67,68 Even without pre-oxidation, a ratio of ~52:44 acrolein:CO 2 was observed, with small amounts of acetaldehyde and propionaldehyde also detected.…”

Risk Assessment of Indoor Formaldehyde and Other Carbonyls in Campus Environments in Northwestern China

“…Symptoms of exposure to acetaldehyde include nausea, vomiting, and headache. Acrolein, an unsaturated carbonyl, is an eye irritant and exacerbates asthma (Arntz et al, 2012). Feng et al (2006) demonstrated that the lung cancer risk was elevated from inhalation of acrolein emitted from ETS.…”

Review on Alternative Route to Acrolein through Oxidative Coupling of Alcohols

“…The catalyst lifetime can be over a dozen years for acrolein production, or shorter when the targeted product is acrylic acid. Indeed, in that It has been produced in the past by the condensation of formaldehyde and acetaldehyde [1,5] (Reaction A, Scheme 1). More recently, there has been a lot of interest in the conversion of glycerol, a co-product of biodiesel and oleochemistry, through double intramolecular dehydration [6] (Reaction C, Scheme 1).…”

“…Acrolein, also known as propenaldehyde, is a synthetic chemical currently produced by propylene selective oxidation (Reaction B, Scheme 1). It is used for the production of fine chemicals such flavor and fragrances and pharmaceutical compounds, including antibiotics and antimicrobials [1][2][3][4]. It is also used in larger quantities to produce methionine (an essential amino acid), and as a non-isolated intermediate to acrylic acid.…”