Abstract:Resistance to bile acids is a necessary ability for bacteria that live in the gastrointestinal tract, such as Helicobacter pylori. The role of the bacterial drug efflux system is important for bile acid tolerance. Using the H. pylori JP26 strain and the JP26AcrB strain deficient in AcrB the relationship between the drug efflux system AcrB and the bile acid tolerance of H. pylori was investigated. Bacterial susceptibility to bile acids was measured by the agar dilution method. To examine the ability to efflux b… Show more
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