Acoustic radiation force impulse: a new ultrasonographic technology for the widespread noninvasive diagnosis of liver fibrosis

Boursier, Jérôme; Isselin, G.; Fouchard-Hubert, I.; Oberti, Frédéric; Dib, Nina; Lebigot, J.; Bertrais, Sandrine; Gallois, Yves; Calès, Paul; Aubé, Christophe

doi:10.1097/meg.0b013e328339e0a1

Cited by 126 publications

(91 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The shear wave velocity (expressed in meters per second) is measured in a region of interest smaller than that of TE (10-mm long and 6-mm wide), but that can be chosen by the examiner. Preliminary results suggest that at least in patients with chronic hepatitis C, its performance is very similar to that of TE, although further validation is warranted [122][123][124][125][126]. The major advantage of this novel technology is that it can be easily implemented on a modified commercial ultrasound machine.…”

Section: Novel Imaging Techniquesmentioning

confidence: 99%

Non-invasive assessment of liver fibrosis in chronic hepatitis C

Castéra

2011

Hepatol Int

View full text Add to dashboard Cite

Section: Novel Imaging Techniquesmentioning

confidence: 99%

Non-invasive assessment of liver fibrosis in chronic hepatitis C

Castéra

2011

Hepatol Int

View full text Add to dashboard Cite

“…The SWV is proportional to the square root of the tissue elasticity [5]. Many of the preliminary studies have yielded comparable results of the ARFI sonoelastographic velocity for determining the severity of liver fibrosis [5][6][7][8].…”

Section: Discussionmentioning

confidence: 99%

“…With the increasing interest in finding new non-invasive methods for evaluating liver cirrhosis patients, ARFI can be applied for the measurement of liver stiffness as an alternative to needle biopsy. Many recent studies have shown that ARFI imaging is an accurate non-invasive modality compared with transient elastography and serum fibrosis marker tests [5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Predicting portal hypertension as assessed by acoustic radiation force impulse: correlations with the Doppler ultrasound

Cho²,

Hj³

et al. 2012

The British Journal of Radiology

View full text Add to dashboard Cite

Objective The purpose of this study was to assess the value of acoustic radiation force impulse (ARFI) for evaluating portal hypertension by correlating the elasticity of liver cirrhosis, as measured by ARFI, with haemodynamic indices measured by Doppler ultrasound. Methods We evaluated the data of a total of 154 prospectively enrolled patients who underwent both duplex Doppler ultrasound and ARFI imaging. The duplex Doppler ultrasound indices, including the mean portal vein velocity, splenic index (SI) and splenoportal index (SPI) were evaluated to determine the statistical correlation with shear wave velocity (SWV) of ARFI. We also analysed the differences in the correlations between the SI, SPI and SWV of the group who had varices. The correlations were assessed with Spearman9s rank correlation coefficients. Results There was an increase of SWV in parallel with the increase of the SI (r50.409, p,0.01) and SPI (r50.451, p,0.01). In the patient group who did not have varices (n574), the Doppler indices were found to be more correlated with the SWV (SI: r50.447, SPI: r50.552, p,0.01). However, the group with varices showed no correlation between the SWV and the Doppler parameters. Conclusion SWV of ARFI was well correlated statistically with Doppler parameters, but is of limited value in predicting portal hypertension directly owing to great variability of Doppler parameters. By evaluating the correlation between ARFI and Doppler ultrasound, we suggest that the SWV might be a non-invasive supplementary tool for predicting portal hypertension.

show abstract

“…The fibrosis scores are defined as follows: 0, no fibrosis; 1, fibrous expansion of some portal areas, with or without short fibrous septa; 2, fibrous expansion of most portal areas, with or without short fibrous septa; 3, fibrous expansion of most portal areas with occasional portal to portal bridging; 4, fibrous expansion of most portal areas with marked bridging (portal to portal as well as portal to central); 5, marked bridging with occasional nodules (incomplete cirrhosis); and 6, cirrhosis, probable or definite. 10 Mean ± standard deviation, median, minimum, and maximum values are used here to describe the quantitative variables. In addition, frequency and percentages are given for nominal data.…”

Section: Methodsmentioning

confidence: 99%

“…The propagation speed (measured in meters per second) increases with the stage of the fibrosis. 6 It has been shown that ARFI is a reliable technique for diagnosing or excluding liver cirrhosis [9][10][11] and shows similar predictive value for significant fibrosis and cirrhosis compared with TE. 6 However, the standard cut off value of the ARFI technique is not yet well established in the clinical care of liver transplant patients.…”

Section: Introductionmentioning

confidence: 99%

Liver Stiffness Measurements Using Acoustic Radiation Force Impulse in Recipients of Living-Donor and Deceased-Donor Orthotopic Liver Transplant

Haberal

Turnaoğlu²,

Özdemır³

et al. 2021

Exp Clin Transplant

View full text Add to dashboard Cite

Objectives: The aim of this study was to evaluate the diagnostic efficiency of the acoustic radiation force impulse (Siemens Medical Solutions, Erlangen, Germany) elastography in assessment of fibrosis in orthotopic liver transplant patients. Materials and Methods:We enrolled 28 orthotopic liver transplant patients (deceased and living donors), whose biopsy decision had been prospectively given clinically. Ten acoustic radiation force impulse elastographic measurements were applied before the biopsy or within 3 days after the biopsy by 2 radiologists. After the core tissue needle biopsy, specimens of all patients were analyzed according to the modified Ishak scoring system. Measurements of acoustic radiation force impulse elastography and pathology specimen results were compared. Key words: Liver biopsy, Liver fibrosis, Metavir, Transient elastography, Ultrasonography IntroductionLiver transplant is the only treatment option for advanced liver disease. However, after liver transplant, acute complications (including primary dysfunction, hepatic artery thrombosis, portal vein thrombosis, hepatic venous obstruction, bile leak, and biliary stricture) or chronic complications (including chronic rejection, disease recurrence, and drug-induced complications) may occur. 1-3 Posttransplant liver dysfunction can have various causes; evaluation of the causes, which can lead to diffuse parenchymal damage, including fibrosis, is of clinical importance.Postoperative B-mode and Doppler ultrasonography (US) are standard procedures for the assessment of graft complications. From US findings, clinical symptoms, and abnormal laboratory findings, a liver biopsy may be required. 4 Although liver biopsy is the standard method for the assessment of morphologic liver changes and fibrosis, it is an invasive procedure that may cause complications. 5 Transient elastography (TE) is currently the most widely used and endorsed method for the asses sment of liver fibrosis in many conditions, such as chronic hepatitis B and C, nonalcoholic steatohepatitis, and nonalcoholic fatty liver disease, as well as in posttransplant patients. 6 Insufficient performance in detecting mild fibrosis, failure to measure liver elasticity in patients with obesity, ascites, and narrow intercostal space, and inability to target liver parenchyma by direct visualization are problems that remain a considerable adversity of this tool. 7,8 Acoustic radiation force impulse (ARFI; Siemens Medical Solutions, Erlangen, Germany) elastography is a new technology to measure liver stiffness and

show abstract

Acoustic radiation force impulse: a new ultrasonographic technology for the widespread noninvasive diagnosis of liver fibrosis

Abstract: ARFI is highly feasible and reproducible, and provides diagnostic accuracy similar to Fibroscan. This new device seems noteworthy for the widespread noninvasive diagnosis of liver fibrosis.

Cited by 126 publications

References 27 publications

Non-invasive assessment of liver fibrosis in chronic hepatitis C

Non-invasive assessment of liver fibrosis in chronic hepatitis C

Predicting portal hypertension as assessed by acoustic radiation force impulse: correlations with the Doppler ultrasound

Liver Stiffness Measurements Using Acoustic Radiation Force Impulse in Recipients of Living-Donor and Deceased-Donor Orthotopic Liver Transplant

Contact Info

Product

Resources

About