Acoustic interaction forces between small particles in an ideal fluid

Silva, Glauber T.; Bruus, Henrik

doi:10.1103/physreve.90.063007

Cited by 122 publications

(114 citation statements)

References 35 publications

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“…The simulation of these phenomena relies on numerically well-characterized acoustic fields, which, we believe, are provided by the model we present here. Possible model strategies to pursue in such calculations were outlined by Muller and Bruus [32], Muller et al [36] and Lei et al [59] for the case of acoustic streaming, by Silva and Bruus [60] for acoustic particle-particle interactions, and by Ley and Bruus [61] for hydrodynamic particle-particle interactions.…”

Section: Discussionmentioning

confidence: 99%

Three-Dimensional Numerical Modeling of Acoustic Trapping in Glass Capillaries

Ley

Bruus

2017

Phys. Rev. Applied

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Acoustic traps are used to capture and handle suspended microparticles and cells in microfluidic applications. A particular simple and much-used acoustic trap consists of a commercially available, millimeter-sized, liquid-filled straight glass capillary actuated by a piezoelectric transducer. Here, we present a three-dimensional numerical model of the acoustic pressure field in the liquid coupled to the displacement field of the glass wall, taking into account mixed standing and traveling waves as well as absorption. The model explains the dynamical mechanism that leads to the formation of localized acoustic resonance modes in such a straight acoustic waveguide without any geometrical cavities in the axial direction of the capillary. The model further predicts that some of these modes are well suited for acoustic trapping, and it provides estimates for their frequencies and quality factors, the magnitude of the acoustic radiation force on a single test particle as a function of position, and the resulting acoustic retention force of the trap. We show that the model predictions are in agreement with published experimental results, and we discuss how improved and more-stable acoustic-trapping modes might be obtained using the model as a design tool.

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Section: Discussionmentioning

confidence: 99%

Three-Dimensional Numerical Modeling of Acoustic Trapping in Glass Capillaries

Ley

Bruus

2017

Phys. Rev. Applied

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“…4 (III)). While a systematic study of multiple particle interaction was beyond the scope of this study, such systems may offer interesting possibilities to probe the accuracy of recent radiation force calculations for multiple-scatterers [42].…”

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confidence: 99%

Observation of a Single-Beam Gradient Force Acoustical Trap for Elastic Particles: Acoustical Tweezers

2016

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We demonstrate the trapping of elastic particles by the large gradient force of a single acoustical beam in three dimensions. Acoustical tweezers can push, pull and accurately control both the position and the forces exerted on a unique particle. Forces in excess of 1 micronewton were exerted on polystyrene beads in the sub-millimeter range. A beam intensity less than 50 Watts/cm 2 was required ensuring damage-free trapping conditions. The large spectrum of frequencies covered by coherent ultrasonic sources provide a wide variety of manipulation possibilities from macroto microscopic length scales. Our observations could open the way to important applications, in particular in biology and biophysics at the cellular scale and for the design of acoustical machines in microfluidic environments.

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“…45 As discussed in the supplementary section S4, the cumulative effect of these factors is lower than 0.5% in our set-up-as used in this study-and was therefore neglected. Like detailed above for the particles, threshold measurements allowed a measurement of the size distribution of the used sample of Expancel after expansion (measured mode diameter: 10.1 lm, measured average diameter: 12.4 lm, 90% percentile: 18.1 lm; see supplementary figure S3).…”

Section: Tracking Of Polystyrene Beads and Polymer-coated Microbubmentioning

confidence: 99%

Acoustic force measurements on polymer-coated microbubbles in a microfluidic device

Memoli

Fury

Baxter

et al. 2017

The Journal of the Acoustical Society of America

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This work presents an acoustofluidic device for manipulating coated microbubbles, designed for the simultaneous use of optical and acoustical tweezers. A comprehensive characterization of the acoustic pressure in the device is presented, obtained by the synergic use of different techniques in the range of acoustic frequencies where visual observations showed aggregation of polymer-coated microbubbles. In absence of bubbles, the combined use of laser vibrometry and finite element modelling supported a non-invasive measurement of the acoustic pressure and an enhanced understanding of the system resonances. Calibrated holographic optical tweezers were used for direct measurements of the acoustic forces acting on an isolated microbubble, at low driving pressures, and to confirm the spatial distribution of the acoustic field. This allowed quantitative acoustic pressure measurements by particle tracking, using polystyrene beads, and an evaluation of the related uncertainties. This process facilitated the extension of tracking to microbubbles, which have a negative acoustophoretic contrast factor, allowing acoustic force measurements on bubbles at higher pressures than optical tweezers, highlighting four peaks in the acoustic response of the device. Results and methodologies are relevant to acoustofluidic applications requiring a precise characterization of the acoustic field and, in general, to biomedical applications with microbubbles or deformable particles. [http://dx

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Acoustic interaction forces between small particles in an ideal fluid

Cited by 122 publications

References 35 publications

Three-Dimensional Numerical Modeling of Acoustic Trapping in Glass Capillaries

Three-Dimensional Numerical Modeling of Acoustic Trapping in Glass Capillaries

Observation of a Single-Beam Gradient Force Acoustical Trap for Elastic Particles: Acoustical Tweezers

Acoustic force measurements on polymer-coated microbubbles in a microfluidic device

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