Acoustic Analysis of Changes in Articulation Proficiency in Patients with Advanced Head and Neck Cancer Treated with Chemoradiotherapy

Jacobi, Irene; Rossum, Maya A. van; Molen, Lisette van der; Hilgers, Frans J. M.; Brekel, Michiel W. M. van den

doi:10.1177/000348941312201205

Cited by 18 publications

(34 citation statements)

References 29 publications

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“…Furthermore, only few studies with adequate pretreatment data collection prospectively investigated changes in patient-and observer-rated voice quality [6,[9][10][11][34][35][36]. Longest follow-up was a year in all.…”

Section: Introductionmentioning

confidence: 99%

Prospective clinical study on long-term swallowing function and voice quality in advanced head and neck cancer patients treated with concurrent chemoradiotherapy and preventive swallowing exercises

Kraaijenga

Molen

Jacobi

et al. 2014

Eur Arch Otorhinolaryngol

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Concurrent chemoradiotherapy (CCRT) for advanced head and neck cancer (HNC) is associated with substantial early and late side effects, most notably regarding swallowing function, but also regarding voice quality and quality of life (QoL). Despite increased awareness/knowledge on acute dysphagia in HNC survivors, long-term (i.e., beyond 5 years) prospectively collected data on objective and subjective treatment-induced functional outcomes (and their impact on QoL) still are scarce. The objective of this study was the assessment of long-term CCRT-induced results on swallowing function and voice quality in advanced HNC patients. The study was conducted as a randomized controlled trial on preventive swallowing rehabilitation (2006-2008) in a tertiary comprehensive HNC center with twenty-two disease-free and evaluable HNC patients as participants. Multidimensional assessment of functional sequels was performed with videofluoroscopy, mouth opening measurements, Functional Oral Intake Scale, acoustic voice parameters, and (study specific, SWAL-QoL, and VHI) questionnaires. Outcome measures at 6 years post-treatment were compared with results at baseline and at 2 years post-treatment. At a mean follow-up of 6.1 years most initial tumor-, and treatment-related problems remained similarly low to those observed after 2 years follow-up, except increased xerostomia (68%) and increased (mild) pain (32%). Acoustic voice analysis showed less voicedness, increased fundamental frequency, and more vocal effort for the tumors located below the hyoid bone (n = 12), without recovery to baseline values. Patients' subjective vocal function (VHI score) was good. Functional swallowing and voice problems at 6 years post-treatment are minimal in this patient cohort, originating from preventive and continued post-treatment rehabilitation programs.

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Section: Introductionmentioning

confidence: 99%

Prospective clinical study on long-term swallowing function and voice quality in advanced head and neck cancer patients treated with concurrent chemoradiotherapy and preventive swallowing exercises

Kraaijenga

Molen

Jacobi

et al. 2014

Eur Arch Otorhinolaryngol

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“…Among the 22 studies, 10 include more than 20 patients, and also 10 include between 2 and 18 subjects . Two articles do not report the number of subjects involved in the acoustic analysis .…”

Section: Resultsmentioning

confidence: 99%

“…Two addressed patients with a tumor extension to the soft palate . The other three relate to the tonsil, alone or in comparison to the area of the base of the tongue …”

Section: Resultsmentioning

confidence: 99%

“…Regarding the size of the tumor, 12 studies (54%) include smaller tumors (T1 + T2) than large ones . Three studies (14%) focus on larger tumors (T3 + T4) .…”

Section: Resultsmentioning

confidence: 99%

“…Surgery was combined with other treatment methods such as radiotherapy or chemotherapy in six studies . Finally, a radiochemotherapy without surgical treatment was performed for the participants of two studies (9%) …”

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Effects of oral and oropharyngeal cancer on speech intelligibility using acoustic analysis: Systematic review

et al. 2019

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Background The development of automatic tools based on acoustic analysis allows to overcome the limitations of perceptual assessment for patients with head and neck cancer. The aim of this study is to provide a systematic review of literature describing the effects of oral and oropharyngeal cancer on speech intelligibility using acoustic analysis. Methods Two databases (PubMed and Embase) were surveyed. The selection process, according to the preferred reporting items for systematic reviews and meta‐analyses (PRISMA) statement, led to a final set of 22 articles. Results Nasalance is studied mainly in oropharyngeal patients. The vowels are mostly studied using formant analysis and vowel space area, the consonants by means of spectral moments with specific parameters according to their phonetic characteristic. Machine learning methods allow classifying “intelligible” or “unintelligible” speech for T3 or T4 tumors. Conclusions The development of comprehensive models combining different acoustic measures would allow a better consideration of the functional impact of the speech disorder.

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Palatal augmentation prostheses in individuals treated for head and neck cancer: Effects on speech and oral transport

2020

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BackgroundNegative side effects affecting articulation and oral transport are common after treatment for head and neck cancer (HNC). The aim of this study was to assess the effects on speech and patient‐reported experience of palatal augmentation prostheses (PAP) in this patient group.MethodsTwenty consecutive patients who had received a PAP were included. We performed a blinded randomized listener assessment of recordings of the patients' speech with and without the PAP. Patient‐reported experiences were collected from medical records.ResultsThe listener assessment showed that production of velar sounds improved significantly for 12 of 19 patients; 12 of 19 patients also reported easier or better speech with the PAP. All six patients treated for tongue cancer reported speech improvement. Seven of 20 patients reported better transport of food or saliva.ConclusionA PAP can help patients treated for HNC to more precisely articulated velar consonants and can benefit oral transport.

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Acoustic Analysis of Changes in Articulation Proficiency in Patients with Advanced Head and Neck Cancer Treated with Chemoradiotherapy

Cited by 18 publications

References 29 publications

Prospective clinical study on long-term swallowing function and voice quality in advanced head and neck cancer patients treated with concurrent chemoradiotherapy and preventive swallowing exercises

Prospective clinical study on long-term swallowing function and voice quality in advanced head and neck cancer patients treated with concurrent chemoradiotherapy and preventive swallowing exercises

Effects of oral and oropharyngeal cancer on speech intelligibility using acoustic analysis: Systematic review

Palatal augmentation prostheses in individuals treated for head and neck cancer: Effects on speech and oral transport

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