Aconitum heterophylum from Kashmir: Evaluation of fatty acid profile, antibacterial, antioxidant activities and functional group analysis

Nengroo, Zubair Rehman; Ganie, Adil Shafi; Azeem, Mohammad Fazle

doi:10.1016/j.carpta.2021.100105

Cited by 3 publications

(2 citation statements)

References 25 publications

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“…Compared to the IR spectrum of PSO reported by Aruna et al (2018), PA had an obvious ‐OH peak around 3301 cm −1 , which is assigned to the hydroxyl group of carboxyl of PA. In addition, PA reserved the stretching peaks of –CH around 2900 cm −1 , –C=O peak of 1713 cm −1 , and bending vibration peak of –CH from methyl at 1462 cm −1 (Nengroo et al, 2021), which were also presented in the spectrum of PSO. Since PSO contains other constituents like fatty acids, sterols, and polyphenols, the spectrum of PSO in the range 1500 to 600 cm −1 looked more complex than that of PA.…”

Section: Resultsmentioning

confidence: 99%

Isolation of punicic acid from pomegranate seed oil by modified freeze crystallization and response surface methodology

Yang

Liu

et al. 2022

Food Processing Preservation

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A modified freeze crystallization method based on the different melting points of fatty acids was employed to isolate punicic acid (PA), a C18 polyunsaturated fatty acid (PUFA), from pomegranate seed oil (PSO). The purification process was optimized by response surface methodology. The complex effects of factors as well as their interactions on the purity, content, and yield of PA were simulated by the second‐order polynomial equations. It indicates that repeated freezing and thawing help to separate PA from the impurities with close melting points. Under the optimum conditions (solvent‐to‐material ratio of 12 ml/g, three freeze–thaw cycles, retaining the last 30% melting fraction), the content and purity of PA reached 950.00 ± 1.38 mg/g and 95.39 ± 0.66%, which were equivalent to 2.54 and 1.21 folds of original sample, respectively. The chemical structure of PA was confirmed by UV, IR, NMR, and GC–MS. PA exhibited a much stronger capacity in inhibiting various bacteria than PSO. Novelty impact statement Freeze crystallization combined with urea complex is a commonly used method to isolate PUFA, which has multiple beneficial effects on human health. However, the procedure is time‐consuming, low yield, and accompanied with potential toxic degradation products from urea. The study provides an efficient, safe, and convenient approach to separate fatty acids with different melting points and holds immerse prospective to be utilized in PUFA manufacture.

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Section: Resultsmentioning

confidence: 99%

Isolation of punicic acid from pomegranate seed oil by modified freeze crystallization and response surface methodology

Yang

Liu

et al. 2022

Food Processing Preservation

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“…Species belonging to the genus Aconitum Laeve ( A. Laeve ) have demonstrated a wide range of pharmacological activities, especially cardiotonic, anti-inflammatory, and analgesic potential [ 43 , 44 ]. The plant A. Laeve is well known for the presence of potent diterpenoid alkaloids that exhibit promising antibacterial, antiviral, and antioxidant activities [ 45 , 46 , 47 ]. The potential of A. Laeve to mediate the reduction of Ag into NPs has not been explored previously.…”

Section: Introductionmentioning

confidence: 99%

Assessing the Potential of Aconitum Laeve Extract for Biogenic Silver and Gold Nanoparticle Synthesis and Their Biological and Catalytic Applications

Ahmad,

Xu,

Tariq

et al. 2024

Molecules

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The adoption of green chemistry protocols in nanoparticle (NP) synthesis has exhibited substantial potential and is presently a central focus in research for generating versatile NPs applicable across a broad spectrum of applications. In this scientific contribution, we, for the first time, examined the ability of Aconitum Laeve (A. Laeve) crude extract to synthesize silver and gold nanoparticles (AgNPs@AL; AuNP@AL) and explored their potential applications in biological activities and the catalytic degradation of environmental pollutants. The synthesized NPs exhibited a distinctive surface plasmon resonance pattern, a spherical morphology with approximate sizes of 5–10 nm (TEM imaging), a crystalline architecture (XRD analysis), and potential functional groups identified by FTIR spectroscopy. The antibacterial activity was demonstrated by inhibition zones that measured 16 and 14 mm for the AgNPs@AL and AuNP@AL at a concentration of 80 µg/mL against Staphylococcus aureus and 14 and 12 mm against Escherichia coli, respectively. The antioxidant potential of the synthesized NPs was evaluated using 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-Oxide (PTIO), and 3-ethylbenzothiazoline-6-sulfonic acid (ABTS) assays. Our findings suggest that the AuNP@AL effectively countered the tested radicals considerably, displaying IC50 values of 115.9, 103.54, and 180.85 µg/mL against DPPH, PTIO, and ABTS, respectively. In contrast, the AgNPs@AL showed IC50 values of 144.9, 116.36, and 95.39 µg/mL against the respective radicals. In addition, both the NPs presented significant effectiveness in the photocatalytic degradation of methylene blue and rhodamine B. The overall observations indicate that A. Laeve possesses a robust capability to synthesize spherical nanoparticles, exhibiting excellent dispersion and showcasing potential applications in both biological activities and environmental remediation.

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Functional and emulsification characteristics of phospholipids and derived o/w emulsions from peony seed meal

Xia

Zhang

et al. 2022

Food Chemistry

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Aconitum heterophylum from Kashmir: Evaluation of fatty acid profile, antibacterial, antioxidant activities and functional group analysis

Cited by 3 publications

References 25 publications

Isolation of punicic acid from pomegranate seed oil by modified freeze crystallization and response surface methodology

Isolation of punicic acid from pomegranate seed oil by modified freeze crystallization and response surface methodology

Assessing the Potential of Aconitum Laeve Extract for Biogenic Silver and Gold Nanoparticle Synthesis and Their Biological and Catalytic Applications

Functional and emulsification characteristics of phospholipids and derived o/w emulsions from peony seed meal

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