Acne detergicans

Mills, O. H.

doi:10.1001/archderm.111.1.65

Cited by 22 publications

(15 citation statements)

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“…The safety of the acidic syndet used here looks even more important, as in the recent literature the term detergent in the context of acne is almost exclusively used in connection with an unwanted effect. Millsand Kligman [19] have even introduced the term acne detergicans. They, however, did not focus on the exact type of skin cleanser used.…”

Section: Discussionmentioning

confidence: 99%

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Einfluß der regelmäßigen Anwendung einer Seife oder eines sauren Syndetwaschstücks auf die Prä-Akne

Ponce-Pöschl²,

Klövekorn³

et al. 1995

Infection

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The role of regular skin cleansing with soap or syndet in pre-acne is ill-defined. The intention of this study was to assess the relative value of an acidic syndet bar and a conventional soap bar in the prevention of acne lesions in acne-prone patients. In a randomized, open, comparative trial the three months' application of either an acidic syndet bar or a conventional soap to facial skin for 1 min each in the morning and in the evening was compared in 120 adolescents and young adults with inflammatory acne grade I or II according to the Plewig and Kligman classification. It was a confirmatory trial with the number of inflammatory lesions being the prime parameter of concern. In addition, non-inflammatory acne lesions were analyzed as were parameters of safety such as itching, redness and scaling. While the number of inflammatory acne lesions, i.e., papulopustules, did not differ in the two trial groups composed of 57 evaluable cases each, this was the case from 4 weeks of application onward: in the group using soap the mean number of inflammatory lesions increased from 14.6 (+/- 5.3) to 15.3 (+/- 6.0), while it decreased in the other group from 13.4 (+/- 5.2) to 10.4 (+/- 5.8) (p < 0.0001). Symptoms or signs of irritation were seen in 40.4% of individuals belonging to the former and 1.8% belonging to the latter group. The number of papulopustules characteristic of inflammatory acne thus is clearly lower when a syndet bar of the acidic type is regularly used for cleansing the face as compared to a (necessarily alkaline) soap.(ABSTRACT TRUNCATED AT 250 WORDS)

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Section: Discussionmentioning

confidence: 99%

“…Thirty-five individuals in the soap group were male and 32 in the synthetic cleanser group. The ages were 19…”

Section: Study Populationmentioning

confidence: 99%

Einfluß der regelmäßigen Anwendung einer Seife oder eines sauren Syndetwaschstücks auf die Prä-Akne

Ponce-Pöschl²,

Klövekorn³

et al. 1995

Infection

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“…According to Dreno et al , cosmetics can be a factor in adult acne when retentional lesions, mainly closed comedones, are numerous and localized specifically on cheeks and the front head [3]. Some cosmetic ingredients elicit comedones: lanolin, petrolatum and certain vegetable oils [27]. …”

Section: Pathogenesis Of Adult Acnementioning

confidence: 99%

The possible role of diet in the pathogenesis of adult female acne

Romańska-Gocka¹,

Woźniak²,

Kaczmarek-Skamira³

et al. 2016

pdia

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Acne in adults is a chronic, increasingly common disease, especially among women. It differs in pathogenesis and clinical presentation from adolescent acne. Acne in adults is associated with Western diet, defined as high consumption of milk, high glycemic load and high calorie intake. Metabolic signals of this diet result in a significant increase in insulin/insulin growth factor 1 serum level and consequently in the molecular interplay of mammalian target of rapamycin complex 1 kinase (mTORC1)/forkhead box protein 1 (FoxO1) mediated nutrient signaling, leading to increased proliferation of keratinocytes, increased lipogenesis and sebum production and finally to aggravation of acne.

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“…Additionally, in the past commonly used soaps and shampoos have been found to be comedogenic when applied to the rabbit ear [ 101 ].…”

Section: Acne Poor Skin Hygiene and Soapsmentioning

confidence: 99%