Acidose lactique par surdosage en metformine après chirurgie pour une fracture de hanche

Contargyris, Claire; Ponchel, C.; Peytel, E.

doi:10.1016/j.pratan.2013.01.001

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2020

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“…Metformin toxicity is rare but may lead to severe acidosis with a mortality rate that can reach 50% [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Metformin-Induced Lactic Acidosis: A Question of Time

Bellefroid

Goffin

Guntz

et al. 2020

Case Reports in Critical Care

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Metformin is an oral antidiabetic largely prescribed in the treatment of type II diabetes. Overdose is associated with life-threatening lactic acidosis. We report the case of the highest metformin concentration ever described secondary to a voluntary suicidal intake. The patient developed a severe lactic acidosis and hemodynamic shock successfully treated with high-flow hemofiltration. Time to start extrarenal epuration is capital to avoid poor evolution.

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“…Metformin toxicity is rare but may lead to severe acidosis with a mortality rate that can reach 50% [ 3 ].…”

Section: Introductionmentioning

confidence: 99%