Acetylcholinesterase biosensor for inhibitor measurements based on glassy carbon electrode modified with carbon black and pillar[5]arene

Pillar[n]arenes at the Chemistry‐Biology Interface

“…Addition of Ag + and Cu 2+ ions generated AgNPs and Cu 2 O particles, respectively. The group prepared an AChE biosensor from their GCE incorporating 2 by treating it with N ‐(3‐dimethylaminopropyl)‐ N ′‐ethylcarbodiimide chloride followed by N ‐hydroxysuccinimide and finally AChE in phosphate buffered saline . The addition of the pillar[5]arene gave an enhanced electrode response to sub‐nanomolar concentrations of the anticholinesterase pesticides malaoxon, methylparaoxon, carbofuran and aldicarb over five orders of magnitude.…”

An acetylcholinesterase biosensor with high stability and sensitivity based on silver nanowire–graphene–TiO2 for the detection of organophosphate pesticides

“…The principle of AChE reactivation by PBS is not understood at this moment and corresponding mechanism needs further investigation. [35][36][37][38] For each test accuracy, the biosensor was allowed to rest in the PBS environment for a period of time aer undergoing OPs inhibition until the catalytic performance is fully reactivated. Aer the biosensor was inhibited by immersion in DDVP, it can be reactivated by being soaked in PBS.…”

Fluorescence-Based Sensing of Pesticides Using Supramolecular Chemistry

“…Because the host was immobilized on the surface of magnetic nanoparticles, pesticide binding was followed by effective magnetic-based pesticide removal (Figure 9B). In another example, electrochemical-based detection of the binding of pesticides to a pillararenes was reported with extremely high sensitivity (Shamagsumova et al, 2015;Hou et al, 2019).…”