Acetogenins from Annona cornifolia and their antioxidant capacity

Lima, Luciana Alves Rodrigues dos Santos; Pimenta, Lúcia Pinheiro Santos; Boaventura, Maria Amélia D.

doi:10.1016/j.foodchem.2010.03.100

Cited by 68 publications

(45 citation statements)

References 22 publications

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“…Due to the possible hazardous effect of synthetic antioxidants, there is an increasing interest in natural antioxidants such as those in fruits and vegetables (Frankel, 2007;Hossain & Rahman, 2010). Epidemiological studies have shown that an increase in fruit intake is associated with a reduced morbidity of cardiovascular disease, some types of cancer, and neurodegenerative diseases (Guo et al, 2003;Reddy, Sreermulu & Raghunath, 2010;Moure et al, 2001;Lima, Pimenta & Boaventura, 2010;Kou et al, 2009). A possible mechanism for this observation has been attributed to the antioxidant activity in fruits (Guo et al, 2003, Moure et al, 2001, Kou et al, 2009.…”

Section: Antioxidantsmentioning

confidence: 99%

A Comparative Study of the Antioxidant Properties of Three Pineapple (Ananas comosus L.) Varieties

Yuris

Siow

2014

Journal of Food Studies

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The objective of this study was to determine the antioxidant activity of different pineapple varieties namely Josephine (Ananas comosus L. var. comosus cv. Josephine), Morris (Ananas comosus L. var. comosus cv. Morris), and Sarawak (Ananas comosus L. var. comosus cv. Sarawak). Different concentrations of methanol, ethanol, and acetone were used to extract the phenolic compounds. Folin Ciocalteu's reagent was used to determine the total phenolic content. The ascorbic acid content of the fruit extracts was determined using the iodine titration method. The antioxidant activity of the pineapples was measured using the 2,2-diphenyl-1-picryhydrzyl (DPPH) radical scavenging assay, the Ferric Reducing Power (FRP) assay and the Ferrous Ion Chelating (FIC) assay. 50% methanol was chosen as the best solvent for extracting the phenolic compounds of the pineapples. Morris pineapple was found to contain the highest TPC (53.8±0.7 mg GAE/100g fruits) and antioxidant activity. This variety was also found to have the highest DPPH scavenging activity (25.2±0.5 mg AA/100g fruits), FRP (29.6 mg GAE/100g fruits) and FIC ability (8%/100g fruits). Despite having a higher TPC than the Sarawak variety, Josephine exhibited a low scavenging activity. Strong positive correlations (R 2 = 0.9943) were observed between the ascorbic acid content and

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Section: Antioxidantsmentioning

confidence: 99%

A Comparative Study of the Antioxidant Properties of Three Pineapple (Ananas comosus L.) Varieties

Yuris

Siow

2014

Journal of Food Studies

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“…Annonaceae species are rich in acetogenin compounds (Craig et al, 1998) exhibit cytotoxic and anti-carcinogenic antioxidant, anti-psoriatic, larvicidal and anthelmintic activities (Martino-Roaro et al, 2008;Jerry, 2008;Feras et al, 1998;Lima et al, 2010;Saelee et al, 2011;Saelee et al, 2011;Kamaraj et al, 2011a,b). Exploration of botanical extract for novel anti-tumor drugs is a significant concern for mankind, as they might prove to be easy and competent approach.…”

Section: Discussionmentioning

confidence: 99%

Anti-cancer efficacy of ethanolic extracts from various parts of Annona Squamosa on MCF-7 cell line

Veerakumar¹,

Amanulla²,

Ramanathan³

2016

J. Pharmacognosy Phytother.

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Medicinal plant extracts are known to possess breast cancer antidote. The present investigation is focused on anticancer efficacy of various parts of Annona squamosa. The organic (ethanol) extracts from various parts of Annona squamosa were prepared using soxhlet apparatus and tested for in vitro anticancer efficacy on Breast cancer cell line MCF-7 by MTT (3-(4, 5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay. The results obtained from MTT assay showed that the inhibitory concentration values of bark, peel and seed were found to be approximately 20, 30 and 10 μg/ml, respectively The ethanolic seed extract had high anticancer activity with IC50 value of 10 ug/ml, reveals that A. squamosa inhibits the proliferation of MCF-7 by inducing apoptosis. The plant investigated has anti-cancer activity; hence further studies should be carried out for the isolation of the lead molecules from the parts of the plant to treat the breast cancer.

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“…Os resultados foram expressos como EC 50 , que é a quantidade de antioxidantes necessária para diminuir em 50% a concentração inicial de DPPH da solução. Dessa forma, quanto menor o valor do EC 50 , menor terá sido o valor do extrato utilizado para reduzir o radical DPPH• e maior a sua atividade antioxidante (Costa et al, 2010;Lima et al, 2010;Sousa et al, 2007;Mariutti & Bragagnolo, 2007;Govidarajan et al, 2003).…”

Section: Atividade Sequestradora Do Radical Dpphunclassified

Análise fitoquímica e atividade fotoprotetora de extrato etanólico de Euphorbia tirucalli Linneau (Euphorbiaceae)

Orlanda

Vale

2015

Rev. bras. plantas med.

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Palavras-chave: Euphorbia tirucalli Linneau, avelós, atividade fotoprotetora A B S T R A C T: P h y t o c h e m i c a l a n a l y s i s a n d p h o t o p r o t e c t i v e a c t i v i t y o f theethanolic extract of Euphorbia tirucalli Linneau (Euphorbiaceae).Euphorbia tirucalli Linneau, popularly known as "avelos", "naked cock" or "naked dog", is used in popular medicinein order to treat cancer, antibiotic and antiviral diseases. Herbal medicines are often employed in order to assist or replace conventional therapies for the treatment of several diseases, including the prevention of the damage caused by ultraviolet radiation. Thus, the aim of this research was to evaluate the photoprotective potential and phytochemical screening of the ethanol extract of the aerial parts of avelos. The photoprotective activity was assessed by in vitrotrials according to the method adapted from Mansur, using the ethanol extract of the aerial parts. The results showed that the phytochemical study revealed the presence of reducing sugars, alkaloids, phenols, flavonoids, tannins, saponins, steroids and triterpenoids in ethanolic fraction. The extract showed antioxidant activity (EC 50 ) of 16,98 ± 0,35 μg.mL -1 , phenolic contents of 96,18 ± 1,33 mg EqAG/g and 63,57 ± 2,74 flavonoids from mg EqC/g that can advantage the photoprotective activity. Assessing the sun protection factor, it can be observed that all the tested concentrations (0,01 to 0,1 μg.mL -1 ) showed potential for photoprotection from ultraviolet radiation with a range of 6,05 to 19,84 FPS, respectively. These results suggest that the ethanol extract of Euphorbia tirucalli Linneau presents possible photoprotective effect.

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Acetogenins from Annona cornifolia and their antioxidant capacity

Cited by 68 publications

References 22 publications

A Comparative Study of the Antioxidant Properties of Three Pineapple (Ananas comosus L.) Varieties

A Comparative Study of the Antioxidant Properties of Three Pineapple (Ananas comosus L.) Varieties

Anti-cancer efficacy of ethanolic extracts from various parts of Annona Squamosa on MCF-7 cell line

Análise fitoquímica e atividade fotoprotetora de extrato etanólico de Euphorbia tirucalli Linneau (Euphorbiaceae)

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