Acetaldehyde-modified-cystine functionalized Zr-MOFs for pH/GSH dual-responsive drug delivery and selective visualization of GSH in living cells

Abstract

In recent years, the construction of drug carriers that integrate diagnosis and treatment has become a new trend.

An Fe‐MIL100 Based Drug Delivery System for pH and Glutathione Dual‐Responsive Drug Release

“…However, the cumulative release of the DOX from MIL100 is 61 % at pH 5 with GSH, suggesting the dual responsive behaviour of drug release with MIL100 [33] . In addition, the increase of the cumulative release of the DOX is consistent with the increase of the GSH concentration in pH 5 condition (Figure 2e), indicating that GSH can stimulate the release of the DOX from the MIL100 because that GSH can consume by Fe(III) [34] …”

“…[33] In addition, the increase of the cumulative release of the DOX is consistent with the increase of the GSH concentration in pH 5 condition (Figure 2e), indicating that GSH can stimulate the release of the DOX from the MIL100 because that GSH can consume by Fe(III). [34] In addition, MIL100 prepared with the different reaction time also has this similar release behavior (Figure S9), but the cumulative release decrease with the increase in reaction time of MIL100 (Figure 2f). This change is consistent with the increasing trend of Fe(III) content with reaction time (Table S1), indicating that more Fe(III) ions released from MIL100 will consume GSH, which is unfavourable to the degradation of MIL100 by GSH.…”

Recent Progress on Luminescent Metal-Organic Framework-Involved Hybrid Materials for Rapid Determination of Contaminants in Environment and Food

“…MOFs have been used or designed to satisfy the demands of various applications over the last decades. The varied structures and exceptional properties also make MOFs enchanting for possible applications, ranging from gas storage [55] to liquid/ solid-phase separation [56,57], sensing [58], drug delivery [59], heterogeneous catalysis [60] and proton conductivity [61].…”

Synthesis of MOFs/GO composite for corrosion resistance application on carbon steel

“…The synthesis process of Mn-MOF is consistent with Cu-MOF: the raw materials are 0.1 mM of 2,2 0 -bca and 0.2 mM of Mn(CH 3 OOH) 2 $4H 2 O, the solvent is DMF solution, and 10 mL of distilled water. The reaction temperature is 80 C and the reaction time was 72 h. Yellow massive crystals were obtained with the formula [Mn 2 (2…”

“…Metal-organic frameworks (MOFs) are coordination polymers constructed from inorganic metals and organic ligands, by changing the metal ions, organic ligands or the interaction between metal ions and organic ligands, MOFs with variable structures can be prepared. [1][2][3][4][5] Graphene (GR) has stable chemical properties and a unique sheet structure. 6,7 Adding GR to a coating can block the penetration of oxygen, water molecules, chloride ions and other corrosive substances into the coating and extend the life of the coating, so becoming an outstanding candidate for anticorrosion coating barrier materials.…”