Accuracy of an automated transthoracic echocardiographic tool for 3D assessment of left heart chamber volumes

Spitzer, Ernest; Ren, Ben; Soliman, Osama Ibrahim Ibrahim; Zijlstra, Felix; Mieghem, Nicolas Van; Geleijnse, Marcel L.

doi:10.1111/echo.13436

Cited by 15 publications

(21 citation statements)

References 23 publications

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“…These The gold standard method used in this study was the results provided by the conventional 3D echocardiographic analysis. 10,11 As this method does not implement a specific tool for LA volume analysis, the agreement between 3D and HM results was not assessed. 12 Nevertheless, taking into account the good results obtained for LV enddiastolic, LV end-systolic, and LVEF, it is not difficult to assume that the accuracy for LA volume would be similar.…”

Section: Discussionmentioning

confidence: 99%

Left ventricular volumes and ejection fraction quantification using an automated three‐dimensional adaptive analytic echocardiographic algorithm in pediatric population

et al. 2018

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Section: Discussionmentioning

confidence: 99%

Left ventricular volumes and ejection fraction quantification using an automated three‐dimensional adaptive analytic echocardiographic algorithm in pediatric population

et al. 2018

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“…To date, several recent publications indicated that HeartModel had strong correlations with the expert manual 3DE and CMR ( r = 0.84–0.97), high reproducibility and shorter analysis time in adult patient group (14, 15). Using the initial version of HeartModel, Tsang and coworkers reported that LVEF was underestimated and automated LVEDV, LVESV and LAV at LVES were overestimated in HeartModel when compared with manual 3DE measurements (14).…”

Section: Discussionmentioning

confidence: 99%

“…Using the initial version of HeartModel, Tsang and coworkers reported that LVEF was underestimated and automated LVEDV, LVESV and LAV at LVES were overestimated in HeartModel when compared with manual 3DE measurements (14). Still, using the improved version of HeartModel with a default setting of 50% for the global LV boundary for automatic contouring, Spitzer and coworkers demonstrated that only LVEDV were underestimated by HeartModel compared to manual 3DE measurements, with no significant differences in LVESV, LVEF and LAV at LVES (15). Nevertheless, these studies were executed in adults with age ranging from 35 to 86 years, and there were no available data for the application of HeartModel in the adolescent population with or without congenital heart disease.…”

Section: Discussionmentioning

confidence: 99%

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Automated left heart chamber volumetric assessment using three-dimensional echocardiography in Chinese adolescents

Luo

Fang

et al. 2017

Echo Res Pract

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BackgroundSeveral studies have reported the accuracy and reproducibility of HeartModel for automated determination of three-dimensional echocardiography (3DE)-derived left heart volumes and left ventricular (LV) ejection fraction (LVEF) in adult patients. However, it remains unclear whether this automated adaptive analytics algorithm, derived from a ‘training’ population, can encompass adequate echo images in Chinese adolescents.ObjectivesThe aim of our study was to explore the accuracy of HeartModel in adolescents compared with expert manual three-dimensional (3D) echocardiography.MethodsFifty-three Chinese adolescent subjects with or without heart disease underwent 3D echocardiographic imaging with an EPIQ system (Philips). 3D cardiac volumes and LVEF obtained with the automated HeartModel program were compared with manual 3D echocardiographic measurements by an experienced echocardiographer.ResultsThere was strong correlation between HeartModel and expert manual 3DE measurements (r = 0.875–0.965, all P < 0.001). Automated LV and left atrial (LA) volumes were slightly overestimated when compared to expert manual measurements, while LVEF showed no significant differences from the manual method. Importantly, the intra- and inter-observer variability of automated 3D echocardiographic model was relatively low (<1%), surpassing the manual approach (3.5–17.4%), yet requiring significantly less analyzing time (20 ± 7 vs 177 ± 30 s, P < 0.001).ConclusionSimultaneous quantification of left heart volumes and LVEF with the automated HeartModel program is rapid, accurate and reproducible in Chinese adolescent cohort. Therefore, it has a potential to bring 3D echocardiographic assessment of left heart chamber volumes and function into busy pediatric practice.

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“…6,9 This is likely due to the selection of images (only images with good image quality were acceptable), and the extensive use of manually corrected endocardial traces. Some studies have reported that HM presents artificially low volumes.…”

Section: Discrepancies In the Previous Hm Literaturementioning

confidence: 99%

Comparison of 3D echocardiographic‐derived indices using fully automatic left ventricular endocardial tracing (heart model) and semiautomatic tracing (3DQ‐ADV)

et al. 2019

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Aims:The availability of a true 3D dataset provides an opportunity for automation of left ventricular (LV) and left atrial (LA) measurements. Although manual and automated measurements of 3D volumes are known to correlate, the variance is an important parameter for the individual patient. The reasons for discrepancies remain unexplained. We hence aim to explain the disagreement between automated and manual LV and LA volumes. Methods and Results:A total of 355 patients underwent standard clinical echo, with offline analysis in both fully-(Heart Model, Philips) and semiautomated (3DQ-Adv, Philips) assessment of routine indices of LV and LA function and shape. Each image was classified according to quality using a 4-point scale as well as the American Society for Echocardiography guidelines for appropriate use of contrast. Bland-Altman plots were used to assess agreement, and t tests were used to assess differences in agreement. Predictors of volume discrepancy were sought with linear regression. Measures of LV and LA volumes were greater with automatic than semiautomatic assessment. The difference in left ventricular end-diastolic volume was dependent on the number of regional wall-motion abnormalities (RWMA) (β = 0.59, P < .04) and image quality (β = 19.71, P = .02). RWMA predicted the difference in left ventricular end-systolic volume (β = 0.83, P < .01) and left atrial end-systolic volume (β = −1.01 P < .01).Conclusion: LV and LA volumes were higher with automatic than semiautomatic assessment. Image quality and RWMA may contribute to this discrepancy. These limitations need to be addressed before fully automatic assessment of 3D echocardiograms can be used in the clinic. K E Y W O R D S3D Echocardiography, left ventricular volumes, LV endocardial border delineation

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Accuracy of an automated transthoracic echocardiographic tool for 3D assessment of left heart chamber volumes

Abstract: The current improved version of the automated adaptive algorithm is accurate for the assessment of left heart chamber volumes, albeit a small underestimation of left ventricular end-diastolic volume is seen, when compared with manual 3D echocardiography.

Cited by 15 publications

References 23 publications

Left ventricular volumes and ejection fraction quantification using an automated three‐dimensional adaptive analytic echocardiographic algorithm in pediatric population

Left ventricular volumes and ejection fraction quantification using an automated three‐dimensional adaptive analytic echocardiographic algorithm in pediatric population

Automated left heart chamber volumetric assessment using three-dimensional echocardiography in Chinese adolescents

Comparison of 3D echocardiographic‐derived indices using fully automatic left ventricular endocardial tracing (heart model) and semiautomatic tracing (3DQ‐ADV)

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