Automated left heart chamber volumetric assessment using three-dimensional echocardiography in Chinese adolescents

Abstract

BackgroundSeveral studies have reported the accuracy and reproducibility of HeartModel for automated determination of three-dimensional echocardiography (3DE)-derived left heart volumes and left ventricular (LV) ejection fraction (LVEF) in adult patients. However, it remains unclear whether this automated adaptive analytics algorithm, derived from a ‘training’ population, can encompass adequate echo images in Chinese adolescents.ObjectivesThe aim of our study was to explore the accuracy of HeartModel in adolescents compared with expert manual three-dimensional (3D) echocardiography.MethodsFifty-three Chinese adolescent subjects with or without heart disease underwent 3D echocardiographic imaging with an EPIQ system (Philips). 3D cardiac volumes and LVEF obtained with the automated HeartModel program were compared with manual 3D echocardiographic measurements by an experienced echocardiographer.ResultsThere was strong correlation between HeartModel and expert manual 3DE measurements (r = 0.875–0.965, all P < 0.001). Automated LV and left atrial (LA) volumes were slightly overestimated when compared to expert manual measurements, while LVEF showed no significant differences from the manual method. Importantly, the intra- and inter-observer variability of automated 3D echocardiographic model was relatively low (<1%), surpassing the manual approach (3.5–17.4%), yet requiring significantly less analyzing time (20 ± 7 vs 177 ± 30 s, P < 0.001).ConclusionSimultaneous quantification of left heart volumes and LVEF with the automated HeartModel program is rapid, accurate and reproducible in Chinese adolescent cohort. Therefore, it has a potential to bring 3D echocardiographic assessment of left heart chamber volumes and function into busy pediatric practice.

Left ventricular volumes and ejection fraction quantification using an automated three‐dimensional adaptive analytic echocardiographic algorithm in pediatric population

“…HM can provide more accurate results than linear and 2D methods, ensuring the optimization of diagnoses . Although time has been not analyzed in this study, previous experienced confirmed that HM saves time …”

“…13 Although time has been not analyzed in this study, previous experienced confirmed that HM saves time. 7,14…”

“…Similar results were found by Luo et al in a study with 53 Chinese patients older (mean age 17 years)than the subjects enrolled in the present study but with similar body mass index (21 kg/m 2 ). They concluded that simultaneous quantification of left heart volumes and LVEF with HM is rapid, accurate, and reproducible in Chinese adolescent cohort and that HM has a potential to bring 3D echocardiographic assessment into busy pediatric practice 14. F I G U R E 4 Linear regression plots showing correlations between 2D and 3D and HM and 3D for left ventricular ejection fraction.…”

Heart Model A.I. Three-Dimensional Echocardiographic Evaluation of Left Ventricular Function and Parameter Setting

“… 4 , 5 Therefore, HM 3DE may have a chance to bridge the gap between the available technology and clinical practice. In recent studies, HM 3DE has been used to evaluate left ventricular systolic function in multiple populations 6 , 13 , 14 and in patients with various heart diseases, 15 but there is no unified standard for the border parameter settings, and there are few studies on Asian populations. Therefore, this study is important and worthy of discussion.…”

Comparison of 3D echocardiographic‐derived indices using fully automatic left ventricular endocardial tracing (heart model) and semiautomatic tracing (3DQ‐ADV)

“…Furthermore, many patients with common cardiovascular issues were excluded. Further studies 8,10,11 have…”