Accumulated ambient air pollution and colon cancer incidence in Thailand

Abstract

This research examined the relationship between colon cancer risks and pollution in various areas of Thailand, using satellites to gather quantities of aerosols in the atmosphere. Bayesian hierarchical spatio-temporal model and the Poisson log-linear model were used to examine the incidence rates of colon cancer standardized by national references; from the database of the National Health Security Office, Ministry of Public Health of Thailand and NASA’s database from aerosol diagnostics model. Modern-Era Retrospective Analysis for Research and Applications, Version 2 (MERRA-2) was used to explore disease-gender-specific spatio-temporal patterns of colon cancer incidences and accumulated air pollution-related cancers in Thailand between 2010 and 2016. A total of 59,605 patients were selected for the study. Due to concerns regarding statistical reliability between aerosol diagnostics model and colon cancer incidences, the posterior probabilities of risk appeared the most in dust PM2.5. It could be interpreted as relative risk in every increase of 10 μg/m3 in black carbon, organic carbon, and dust-PM2.5 levels were associated respectively with an increase of 4%, 4%, and 15% in the risks of colon cancer. A significant increase in the incidence of colon cancer with accumulated ambient air quality raised concerns regarding the prevention of air pollution. This study utilized data based on the incidences of colon cancer; the country’s database and linked cancer data to pollution. According to the database from NASA’s technology, this research has never been conducted in Thailand.

Predictive MERRA-2 aerosol diagnostic model for oral, oropharyngeal and laryngeal cancer caused by air pollution in Thai population

“…These methods are advantageous for understanding risk factors involving geographic locations that were affected by the incidences of oral, oropharyngeal, and laryngeal cancer in Thailand from various locations in 2017. The definite effect-time of more than 5 years of exposure to air pollution was shown to increase mortality of respiratory disease, lung cancer, colon cancer and cardiovascular disease [41] , [42] , [43] . The developed design of this study is also possible to confirm with the cancer association regarding risk factors in various areas for more than 5 years of exposure; pollution detection in general.…”

Klimakrise: Welche gastroenterologischen Folgeerkrankungen dieses medizinischen Notfalls sollten wir kennen?

“…Neben eigentlichen meteorologischen Faktoren konnte in einer großen europäischen Studie ein Zusammenhang zwischen der Häufigkeit des Magenkarzinoms und einer langfristigen Exposition gegenüber schwefelhaltigem PM2.5 nachgewiesen werden [37]. Ebenso gibt es Hinweise, dass schlechte Luftqualität die Inzidenz des Kolonkarzinoms ungünstig beeinflusst [38]. Es bleibt dabei natürlich unbestritten, dass andere (ebenfalls vermeidbare oder behandelbare) Risikofaktoren zur steigenden Inzidenz dieser Tumoren beitragen [39].…”

Exposome approach for identifying modifiable factors for the prevention of colorectal cancer

“…Common internal risk factors include inflammation, dynamics of gut microbiota 5,6 , genetics 7 , age 8 , sex 9 , and race/ethnicity 9 . Various external exposures such as diet, smoking, drinking [10][11][12][13] , cancer screening 14 , socioeconomic status (SES, 15,16 , social support 17 , industrial pollution 18,19 , and other factors are associated with CRC events.…”