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Russia is characterized by differences in the level of development of regions, the quality of life of the population. According to the World Bank, Russia ranks third in the world in terms of regional inequality. The quality of life is one of the most important indicators recognized by the UN, characterizing the level of development of countries and nations. For Russia, the issue of assessing the quality of life in the regions under the current sanctions conditions is of particular importance. The purpose of the study is to study the role and significance of GRP in the socio-economic development of regions, in shaping the standard of living of the population, and to establish the relationship between GRP and other indicators. In the absence of a unified methodology, the RIRATING rating agency conducts a quality of life rating based on more than 70 indicators, but this list does not include GRP. The peculiarity of the author's approach: GRP is considered as the most important, initial indicator, on the value of which the standard of living of the population depends. The information base of the study was the data of the rating agency, methods were used: analysis and synthesis, grouping, comparison, collation, index, tabular, generalization, etc. The study established the impact of GRP on the quality of life. At the same time, high GRP values do not indicate the efficiency of the region's economy; they do not in themselves provide a high standard of living for the population, since the quality of life is a whole range of interrelated indicators.
Russia is characterized by differences in the level of development of regions, the quality of life of the population. According to the World Bank, Russia ranks third in the world in terms of regional inequality. The quality of life is one of the most important indicators recognized by the UN, characterizing the level of development of countries and nations. For Russia, the issue of assessing the quality of life in the regions under the current sanctions conditions is of particular importance. The purpose of the study is to study the role and significance of GRP in the socio-economic development of regions, in shaping the standard of living of the population, and to establish the relationship between GRP and other indicators. In the absence of a unified methodology, the RIRATING rating agency conducts a quality of life rating based on more than 70 indicators, but this list does not include GRP. The peculiarity of the author's approach: GRP is considered as the most important, initial indicator, on the value of which the standard of living of the population depends. The information base of the study was the data of the rating agency, methods were used: analysis and synthesis, grouping, comparison, collation, index, tabular, generalization, etc. The study established the impact of GRP on the quality of life. At the same time, high GRP values do not indicate the efficiency of the region's economy; they do not in themselves provide a high standard of living for the population, since the quality of life is a whole range of interrelated indicators.
IIntriduction. Complex rehabilitation programs makes an important role in improving exercise tolerance and patients functional status with cardiovascular pathology.Aim. To study the physical rehabilitation effect on the functional status, pro-inflammatory cytokines levels and cardiovascular inflammation biomarker (high-sensitivity C-reactive protein) in heart failure patients with different ejection fractions.Materials and methods. The study included 160 patients with chronic heart failure (84 men and 76 women, mean age 69.4 ± 8.8 years). Two groups of patients with preserved and reduced left ventricular ejection fraction were identified. The groups were divided into two subgroups: the first – those who underwent physical rehabilitation for a year and received standard drug therapy; the second one received exclusively standard drug therapy. At inclusion and after a year of observation, patients were examined: determination of functional status, levels of pro-inflammatory cytokines, serum hs-C-reactive protein, NT-proBNP.Results. Regardless of left ventricular ejection fraction, in the studied patients subgroups undergone physical rehabilitation, a statistically significant decrease in the proinflammatory cytokines levels, NT-proBNP and hs-C-reactive protein was noted. The study also demonstrated the physical rehabilitation beneficial effects on the patients with HF functional status. Thus, the distance walked within 6 minutes and its relation to the proper indicator in patients who underwent physical rehabilitation increased in comparison with the initial indicators during the initial examination of patients and in comparison with control subgroups. This may indicate the positive properly selected physical activity impact on circulatory compensation and the HF course.Conclusion. Carrying out physical rehabilitation for chronic heart failure leads to an improvement in functional status, a decrease in the NT-proBNP, pro-inflammatory cytokines and high-sensitivity C-reactive protein level in comparison with the results of managing patients on drug therapy (without rehabilitation).
The article presents approaches to monitoring and assessing social aspects of regional systems with identification of elements of the health system and demographic components that potentially affect the economic efficiency of functioning of territories. The relevance of the article is determined by objective features of the development of mesoterritories. The analysis of spatial features of the systems’ functioning was conducted on the materials of the Central Federal District. The purpose of the study is to assess the features of the regional genesis using regression analysis and the resulting indicator – gross regional product (hereinafter referred to as GRP), which allows us to give a more reliable characterisation of the mesoterritorial transformation. The subjects were grouped according to the quality of medical and demographic characteristics on the basis of the cluster analysis with further allocation of flagship, catching-up and lagging regions. To substantiate the reliability of the territories’ affiliation to a specific cluster group, a statistical analysis was performed on average values with consideration to identification of the level of medical and demographic development. The conclusion is made about the influence of some factor criteria on the regional space with the construction of a scatter plot. It displays the affiliation to the selected confidence interval and distribution of the elements of the set in the plane between the resulting and factor values, describing the dependence of the GRP on the medical and demographic indicator. These econometric and analytical models can be used by regional governments in the process of strategic planning.
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