Acceptance or Rejection of the COVID-19 Vaccine: A Study on Iranian People’s Opinions toward the COVID-19 Vaccine

Nakhostin-Ansari, Amin; Zimet, Gregory D.; Khonji, Mohammad Saeid; Aghajani, Faezeh; Teymourzadeh, A; Kazerooni, AmirAli Rastegar; Pirayandeh, Pendar; Aghajani, Reyhaneh; Safari, Sepideh; Khalaj, Kamand; Memari, Amir Hossein

doi:10.3390/vaccines10050670

Cited by 10 publications

(11 citation statements)

References 56 publications

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“…However, only one study was conducted in each of the following countries; Republic of Congo ( 59 ), Japan ( 60 ), Poland ( 10 ), Cameroon ( 7 ), Israel ( 61 ), Mexico ( 62 ), Malta ( 63 ), Scotland ( 6 ), Indonesia ( 64 ), England ( 65 ), South Korea ( 66 ), Iran ( 67 ), Nigeria ( 68 ), Tunisia ( 69 ), Netherlands ( 70 ), Thailand ( 71 ), Vietnam ( 72 ), United Arab Emirates ( 73 ), Botswana ( 74 ), Sudan ( 75 ), Czechia ( 76 ), Uganda ( 77 ), France ( 78 ), and in Egypt ( 79 ).…”

Section: Resultsmentioning

confidence: 99%

Global COVID-19 vaccine acceptance rate: Systematic review and meta-analysis

Mengistu

Demmu

Asefa

2022

Front. Public Health

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BackgroundA vaccine against COVID-19 is a vital tool in managing the current pandemic. It is becoming evident that an effective vaccine would be required to control COVID-19. Effective use of vaccines is very important in controlling pandemics and paving the way for an acceptable exit strategy. Therefore, this systematic review and meta-analysis aims to determine the global COVID-19 acceptance rate that is necessary for better management of COVID-19 pandemic.MethodsThis review was conducted based on Preferred Reporting Items for Systematic Reviews and Meta-Analysis protocols and considered the studies conducted on acceptance and/or hesitancy of COVID-19 vaccine. Articles were searched using electronic databases including PubMed, Scopus, Web of Science, Embase, CINAHL, and Google Scholar. The quality of the study was assessed using the Joanna Briggs Institute (JBI) critical assessment tool to determine the relevance of each included article to the study.ResultsOf the 6,021 articles identified through the electronic database search, 68 articles were included in the systematic review and meta-analysis. The global pooled acceptance rate of the COVID-19 vaccine was found to be 64.9% [95% CI of 60.5 to 69.0%]. Based on the subgroup analysis of COVID-19 vaccine acceptance rate by the World Health Organization's region, the countries where the study was conducted, occupation, and survey period, the prevalence of COVID-19 vaccine acceptance rate was 60.8% [95% CI: 56.3, 65.2%], 61.9% [95% CI: 61.3, 62.4%], 81.6% [95% CI: 79.7, 83, 2%] and 64.5% [95% CI: 60.3, 68.5%], respectively.ConclusionsThis review revealed the variation in the level of COVID-19 vaccine acceptance rate across the world. The study found that the overall prevalence of COVID-19 vaccine acceptance was 64.9%. This finding indicated that even if the COVID-19 vaccine is developed, the issue of accepting or taking the developed vaccine and managing the pandemic may be difficult.

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Section: Resultsmentioning

confidence: 99%

Global COVID-19 vaccine acceptance rate: Systematic review and meta-analysis

Mengistu

Demmu

Asefa

2022

Front. Public Health

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“…Various studies have tried to evaluate attitude and willingness toward the COVID‐19 vaccine. In total, attitude toward vaccination against COVID‐19 among Iranian has been reported positive regardless of the vaccine type, from about 70% acceptance rate to more than 80% acceptance rate, which is slightly more than the global willingness 23–27 . Reportedly, misinformation and lack of knowledge contribute to hesitancy and negative attitudes toward COVID‐19 vaccination 23,28,29 …”

Section: Introductionmentioning

confidence: 99%

“…In total, attitude toward vaccination against COVID-19 among Iranian has been reported positive regardless of the vaccine type, from about 70% acceptance rate to more than 80% acceptance rate, which is slightly more than the global willingness. [23][24][25][26][27] Reportedly, misinformation and lack of knowledge contribute to hesitancy and negative attitudes toward COVID-19 vaccination. 23,28,29 Due to the extensive mortality of COVID-19, the health authorities approved emergency administration of the COVID-19 vaccines worldwide.…”

Section: Introductionmentioning

confidence: 99%

“…[23][24][25][26][27] Reportedly, misinformation and lack of knowledge contribute to hesitancy and negative attitudes toward COVID-19 vaccination. 23,28,29 Due to the extensive mortality of COVID-19, the health authorities approved emergency administration of the COVID-19 vaccines worldwide. However, many aspects and features of these vaccines, especially COVAXIN and Sputnik V, are under the shadow of uncertainty.…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of response to different COVID‐19 vaccines in vaccinated healthcare workers in a single center in Iran

Pourakbari

Mirbeyk

Mahmoudi

et al. 2022

Journal of Medical Virology

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Due to the recent coronavirus disease 2019 (COVID-19) pandemic and emergent administration of various vaccines worldwide, comprehensive studies on the different aspects of vaccines are in demand. This study evaluated antibody response after the second dose of the COVID-19 vaccine in the Children's Medical Center personnel. The blood samples of 174 healthcare workers were gathered at least 10 days after vaccination. The administered vaccines included Oxford/AstraZeneca, COVAXIN, Sinopharm, and Sputnik V. This study assessed all antibodies employing ELISA methods, including anti-SARS-CoV-2 neutralizing antibody by DiaZist and Pishtazteb kits, anti-SARS-CoV-2-nucleocapsid by Pishtazteb kit, and anti-SARS-CoV-2-Spike by Razi kit. The cutoff for the tests' results was calculated according to the instructions of each kit. Totally, 174 individuals with an average age of 40 ± 9years participated in this study, the proportion of men was 31%, and the frequency of past COVID-19 infection was 66 (38%). Sixteen (9%) personnel received Oxford/AstraZeneca, 28 (16%) COVAXIN, 29 (17%) Sinopharm, and 101 (58%) Sputnik V. anti-SARS-CoV-2-nucleocapsid and anti-SARS-CoV-2-Spike were positive in 37 (21%), and 163 (94%) participants and their mean level were more in adenoviral-vectored vaccines (p value < 0.0001). Neutralizing antibody was positive in 74% using Pishtazteb kit while 87% using DiaZist kit. All antibodies' levels were significantly higher in those with a past COVID-19 infection (p value < 0.0001). In conclusion, Oxford/AstraZeneca and Sputnik V had a similar outcome of inducing high levels of anti-SARS-Cov-2-spike and neutralizing antibodies, which were more than Sinopharm and COVAXIN. The titers of Anti-SARS-CoV-2-nucleocapsid antibody were low in all of these four vaccines.

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“…Another study in Turkey showed that most of the study participants (66.1%) refused to receive foreign vaccines and were typically willing to receive domestic vaccines [8]. A study on 1928 participants in Iran showed that 69% of the participants were willing to receive vaccines, and female gender, lower educational attainment, and loss of relatives due to COVID-19 infection were signi cantly related to the negative attitudes regarding vaccination [9]. Abbasi et al showed that only a small number of Iranian people with multiple sclerosis were hesitant against COVID-19 vaccination (6.9%), while the majority accepted vaccination [10].…”

Section: Introductionmentioning

confidence: 99%

Investigating the reasons for COVID-19 vaccination refusal in Ahvaz, Iran: A cross-sectional study

Afshari

Alavi

Abedi

et al. 2022

Preprint

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Background Around 70% of the Iranian population had received two doses of COVID-19 vaccines by the end of 2021. In this study we evaluated the reasons of vaccination refusal among people in Ahvaz, Iran. Methods In this cross-sectional study, 800 participants (400 had been vaccinated and 400 had not) were recruited. A demographic questionnaire was completed by interview. The participants who had not received vaccination were asked about the reasons of their refusal, and their answers were recorded. The Shapiro-Wilk test, the independent t-test, Chi-square test, and logistic regression were used for analyzing data. Results Older people were 1.018 times more likely to refrain from vaccination (95% CI: 1.001–1.039). People who were manual workers as well as those who were unemployed/ housewife were .288 and .423 times less likely to receive vaccination, respectively. Illiterate people, and those with high school education were 0.029, and .319 times less likely to receive vaccination (95% CI: 0.007–0.119, and .198-.515, respectively). Participants who had hypertension or suffered from neurological disorders were more likely to receive vaccination. Finally, people affected with severe COVID-19 infection were 3.157 times more likely to get vaccinated (95% CI: 1.672–5.961). Having no trust in the ten existing vaccines in Iran and unacceptance of vaccination were among the top reasons for refusal of vaccination. Conclusion The results of this study showed that lower level of education and older age were contributed to reluctance for vaccination, while having chronic diseases or being already infected with severe COVID-19 infection were associated with more acceptance of vaccination.

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Acceptance or Rejection of the COVID-19 Vaccine: A Study on Iranian People’s Opinions toward the COVID-19 Vaccine

Cited by 10 publications

References 56 publications

Global COVID-19 vaccine acceptance rate: Systematic review and meta-analysis

Global COVID-19 vaccine acceptance rate: Systematic review and meta-analysis

Evaluation of response to different COVID‐19 vaccines in vaccinated healthcare workers in a single center in Iran

Investigating the reasons for COVID-19 vaccination refusal in Ahvaz, Iran: A cross-sectional study

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