Accelerometer-measured light-intensity physical activity and the risk of cardiovascular disease or death in older adults: A meta-analysis

Abstract

Background: Light-intensity physical activity (LPA) is related to a reduced risk of all-cause death in older adults, but its effect on cardiovascular disease or death remains questioned. This meta-analysis aimed to quantify the association of LPA with the risk of cardiovascular disease and death in older adults. Methods:We conducted a literature search in electronic databases for prospective cohort studies assessing the relationship between LPA measured by accelerometers and the risk of cardiovascular disease and/or death in adults aged ≥60 years. Study-specific hazard ratios (HRs) and 95% confidence intervals (CIs) were pooled using a random effects model. Results:Of the 518 articles identified, 5 prospective cohort studies were included. The mean body mass index of included participants was all over 25 kg/m 2 . Pooled results showed that the summary HR per 60 min/day higher of LPA was 0.90 (95% CI, 0.83-0.98; n = 3) for the risk of cardiovascular disease and 0.59 (95% CI, 0.49-0.72; n = 2) for cardiovascular death. Both the relationship of LPA with the risk of cardiovascular disease and cardiovascular death were linearly and inversely shaped. The HR for the risk of cardiovascular disease was greater for LPA than for moderate-to-vigorous physical activity (MVPA), in either equal time or equal amount scale (both P interaction <0.01); but the HR for the risk of cardiovascular death was comparable between LPA and MVPA in both scales (both P interaction ≥0.20). Conclusions:Higher LPA is associated with a reduced risk of cardiovascular disease and death in older adults.

Leisure-time and occupational physical activity and risk of cardiovascular disease incidence: a systematic-review and dose-response meta-analysis of prospective cohort studies

“…According to the available evidence, it seems that the duration of physical activity has a quite important impact on the reduction of CVD risk [ 151 ] but the intensity of exercise should be adapted to the cardiorespiratory capacity and medical conditions of the individual [ 134 ]. A meta-analysis of 5 cohort studies that measured the intensity of physical activity by an accelerometer in older adults found that HR for CVD risk was lower in moderate-to-vigorous physical activity than light-intensity physical activity although HR for CVD death was almost equal in light- and moderate-to-vigorous intensity physical activity [ 152 ], suggesting that moderate-to-vigorous intensity physical activity may be more beneficial for CVD incidence than light-intensity activity.…”

Association of Accelerometer-Measured Sedentary Time and Physical Activity with Arterial Stiffness and Vascular Aging in the General Spanish Population, Analyzed by Sex

“…Sedentary behaviours have an adverse impact on health, regardless of physical activity, increasing mortality by all causes, including by cardiovascular diseases, the risk of cancer, the risk of metabolic disorders such as diabetes mellitus, hypertension and dyslipidaemia, the risk of musculoskeletal disorders such as arthralgia and osteoporosis, and the risk of depression and cognitive deterioration [ 2 , 3 , 4 ]. On the contrary, it has been shown that the more time spent doing physical activity, regardless of the type and intensity, the lower the morbidity and mortality due to cardiometabolic diseases, tumours and mental disorders, with an improvement in the quality of life and the benefits for the health system and society [ 5 , 6 , 7 , 8 , 9 , 10 , 11 ].…”