Accelerated binocular rivalry with anxious personality

Effects of selective 5-HT1A agonist tandospirone on the rate and rhythmicity of binocular rivalry

“…In the study of Nagamine et al( 2007) which reported a relationship between binocular rivalry and anxiety, they suggested that binocular rivalry and anxiety may share some common serotonergic neural substrates. Serotonin has been believed to be an important modulator of anxiety-related circuits (Lowry et al 2005), and Gray and McNaughton (2000) postulated that serotonergic projection from the raphe nucleus to the septo-hippocampal system is an important part of the neural basis of anxiety, reflecting a behavioral inhibitory system.…”

“…Based upon these results, they suggested that psilocybin's effect on binocular rivalry is unlikely to be mediated by the 5-HT 2A receptor. Nagamine et al (2007) explored the relationship between binocular rivalry and anxiety, a state thought to be associated with serotonergic neural activity (Lowry et al 2005). They demonstrated that the perceptual alternation rate in binocular rivalry was accelerated in anxious subjects, and they suggested that binocular rivalry and anxiety may share some common serotonergic neural substrates.…”

Difference in the binocular rivalry rate between depressive episodes and remission

“…This study suggests the involvement of serotonin pathways in neural processing related to binocular rivalry. Subsequently, Nagamine et al [13] have explored the rivalry rate in subjects with various degrees of anxious temperament. Anxiety is a state thought to be associated with dysfunctional serotonergic neural activity [14].…”

The relationship between social anxiety and the perception of depth-ambiguous biological motion stimuli is mediated by inhibitory ability

“…We had originally hypothesized this based on the previous observations that more anxious individuals have greater perceptual reversal rates for ambiguous visual stimuli (Anderson et al, 2013;Li et al, 2000;Meldman, 1965;Meredith, 1967;Nagamine et al, 2007) and that more anxious people have difficulty with inhibitory control (Eysenck & Derakshan, 2011;Eysenck et al, 2007). Here, our rationale was that more socially anxious people would have difficulty inhibiting the more threatening (i.e., facing-towards) percept of depth-ambiguous biological stimuli.…”

“…For example, there is evidence that more anxious participants have significantly faster perceptual reversal rates during binocular rivalry tasks than those who are less anxious (Anderson et al, 2013;Meredith, 1967;Nagamine et al, 2007) and also while viewing static ambiguous figures such as the Schroeder staircase (Li et al, 2000). Furthermore, individuals with clinically significant anxiety have been found to have faster reversal rates than healthy controls before receiving treatment but not afterwards (Meldman, 1965).…”