Acaricidal efficacy of topical formulation of fipronil in naturally infested dogs in Amazonic region, Brazil

Abstract

This study was conducted to show the effectiveness of a novel formulation of fipronil in a spot-on formulation for the therapeutic and preventive control of Rhipicephalus sanguineus in naturally infested dogs. Ticks on all dogs were counted at the moment of treatment and weekly after treatment (therapeutic efficacy) or infestation (preventive efficacy). The profile of the therapeutic efficacy for Rhipicephalus sanguineus suggested that the formulation was able to control the Ixodid species for at least 42 days after the treatment.Keywords: Therapeutic and preventive effectiveness, fipronil, Rhipicephalus sanguineus. ResumoEste estudo teve como objetivo avaliar a eficácia de uma nova formulação "spot-on" à base de fipronil na terapêutica e prevenção do parasitismo por Rhipicephalus sanguineus em cães naturalmente infestados. Foi realizada contagem dos carrapatos no momento da aplicação do produto e semanalmente após o tratamento (eficácia terapêutica), bem como avaliando sua reinfestação (eficácia preventiva). Perfis terapêuticos e preventivos sugerem que a formulação controla o parasitismo por R. sanguineus em cães por pelo menos 42 dias após o tratamento.Palavras-chave: Eficácia terapêutica e preventiva, fipronil, Rhipicephalus sanguineus.

The effectiveness of acaricidic drugs based on herbal raw material

“…For more than a century the control over the number of ixodes ticks has been of a considerable interest to scientists and researchers (Fischer et al, 2013;Dumont et al, 2015). It is now known that the use of chemicals has led to the development of resistance of ixodes ticks to acaricides and the evidence of these facts is increasingly displayed in the modern scientific literature (Abbas et al, 2014).…”