AC Magnetic Technique to Measure Specific Absorption Rate of Magnetic Nanoparticles

Гудошников, С.А.; Liubimov, B.Ya.; Sitnov, Yu. S.; Skomarovsky, V.S.; Usov, N. A.

doi:10.1007/s10948-012-1941-2

Cited by 19 publications

(16 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Figure 5 shows DC magnetization curves measured at room temperature by vibrating sample magnetometer (VSM) for samples I and II dispersed in water with nanoparticle concentrations written on table 1 (same as for the SAR measurements). The absence of coercive field indicates that they are in the superparamagnetic (SPM) regime and hence, the magnetization, M SPM can be described by the Langevin function (see equation 13) integrated for all sizes [32,33]: Fitting the experimental data to equation (13), the values of mean nanoparticle sizes d 0 VSM and the standard deviations σ VSM can be obtained (note the superscript VSM). From the saturation magnetization M sat and the measured volume fractions, the domain magnetization M d can be obtained by means of equation (12).…”

Section: Linear Response Theorymentioning

confidence: 99%

“…In fact, it will be shown that the standard deviation σ that best fit experimental SAR values is always bellow σ VSM . Table 3: Parameters that best fit the measured DC magnetization curves in figure 7 using equation (13). Next columns: Average sizes, standard size deviation and polydispersity index (p.i.…”

Section: Linear Response Theorymentioning

confidence: 99%

“…The magnetization of polydisperse non-interacting superparamagnetic nanoparticles, M SPM is given by equation (13) in the previous section. For small applied magnetic field H app typical of FC/ZFC experiments, the Langevin function can be simplified to L(x) ≈ x/3.…”

Section: Zero-field Cooled (Zfc) Magnetization As a Function Of Tempementioning

confidence: 99%

“…DC magnetization curves measured by VSM. Solid lines indicate the fitting of experimental data to equation(13).…”

mentioning

confidence: 99%

See 3 more Smart Citations

Specific absorption rate dependence on temperature in magnetic field hyperthermia measured by dynamic hysteresis losses (ac magnetometry)

Garaio¹,

Sandre

Collantes³

et al. 2014

Nanotechnology

View full text Add to dashboard Cite

Magnetic nanoparticles (NPs) are intensively studied for their potential use for magnetic hyperthermia, a treatment that has passed a phase II clinical trial against severe brain cancer (glioblastoma) at the end of 2011. Their heating power, characterized by the 'specific absorption rate (SAR)', is often considered temperature independent in the literature, mainly because of the difficulties that arise from the measurement methodology. Using a dynamic magnetometer presented in a recent paper, we measure here the thermal dependence of SAR for superparamagnetic iron oxide (maghemite) NPs of four different size-ranges corresponding to mean diameters around 12 nm, 14 nm, 15 nm and 16 nm. The article reports a parametrical study extending from 10 to 60 °C in temperature, from 75 to 1031 kHz in frequency, and from 2 to 24 kA m(-1) in magnetic field strength. It was observed that SAR values of smaller NPs decrease with temperature whereas for the larger sample (16 nm) SAR values increase with temperature. The measured variation of SAR with temperature is frequency dependent. This behaviour is fully explained within the scope of linear response theory based on Néel and Brown relaxation processes, using independent magnetic measurements of the specific magnetization and the magnetic anisotropy constant. A good quantitative agreement between experimental values and theoretical values is confirmed in a tri-dimensional space that uses as coordinates the field strength, the frequency and the temperature.

show abstract

Section: Linear Response Theorymentioning

confidence: 99%

Section: Linear Response Theorymentioning

confidence: 99%

Section: Zero-field Cooled (Zfc) Magnetization As a Function Of Tempementioning

confidence: 99%

“…DC magnetization curves measured by VSM. Solid lines indicate the fitting of experimental data to equation(13).…”

mentioning

confidence: 99%

See 2 more Smart Citations

Specific absorption rate dependence on temperature in magnetic field hyperthermia measured by dynamic hysteresis losses (ac magnetometry)

Garaio¹,

Sandre

Collantes³

et al. 2014

Nanotechnology

View full text Add to dashboard Cite

show abstract

“…Only a few of the therapies have indicated clinical success. It is difficult identifying the ideal drug delivery system for the various types of novel drugs with diverse physiological features and varying levels of therapeutic activities (Gudoshnikov et al 2012, Gudoshnikov et al 2013). …”

Section: Methodsmentioning

confidence: 99%

Magnetic nanoparticles in cancer diagnosis and treatment: a review

Karkan

Mohammadhosseini

Panahi

et al. 2016

Artificial Cells, Nanomedicine, and Biotechnology

View full text Add to dashboard Cite

Diagnosis and treatment of lung cancer have been characterized with a variety of challenges. However, with the advancement in magnetic nanoparticle (MNP) technology, many challenges in the diagnosis and treatment of lung cancer are on the decline. The MNPs have led to many break-through in cancer therapy. This paper seeks to establish the role of MNPs in diagnosis and treatment of lung cancer. It proposes that the existing challenges in the diagnosis and treatment of lung cancer can be addressed through application of MNPs in the process.

show abstract

Magnetic Fluid Hyperthermia Based on Magnetic Nanoparticles: Physical Characteristics, Historical Perspective, Clinical Trials, Technological Challenges, and Recent Advances

Etemadi

Plieger

2020

Advanced Therapeutics

View full text Add to dashboard Cite

Advances in nanotechnology have resulted in the introduction of magnetic fluid hyperthermia (MFH), a promising noninvasive therapeutic localized cancer treatment. Exposure of a fluid of superparamagnetic iron oxide nanoparticles (IONPs) to an alternating magnetic field (AMF) operating at biologically benign conditions leads to heat dissipation within the tumor and ultimate apoptosis and/or necrosis. Despite use in a clinical setting, there are still impediments preventing widespread use of MFH. These include insufficient heat dissipation potency of IONP fluid, inadequate dose or concentration of deposited fluid to the tumor, inhomogeneous distribution of fluid inside the tumor, the lack of control of real‐time monitoring of temperature rises during treatment, and exposure of the patients to X‐ray radiation produced by computed tomography (CT) scans. Accordingly, massive efforts have been put forth to promote the successful clinical adoption of MFH. In this contribution, the technique of MFH is described, including the present state of clinical MFH. The physical mechanisms behind heat dissipation by magnetic nanoparticles (MNPs) that instigate cell death pathways are discussed, as is recent technological progress in the field toward the advancement of MFH. Finally, an outlook on the future considerations required to accelerate the clinical adoption of MFH is presented.

show abstract

AC Magnetic Technique to Measure Specific Absorption Rate of Magnetic Nanoparticles

Cited by 19 publications

References 8 publications

Specific absorption rate dependence on temperature in magnetic field hyperthermia measured by dynamic hysteresis losses (ac magnetometry)

Specific absorption rate dependence on temperature in magnetic field hyperthermia measured by dynamic hysteresis losses (ac magnetometry)

Magnetic nanoparticles in cancer diagnosis and treatment: a review

Magnetic Fluid Hyperthermia Based on Magnetic Nanoparticles: Physical Characteristics, Historical Perspective, Clinical Trials, Technological Challenges, and Recent Advances

Contact Info

Product

Resources

About