AC electroosmotic generated in-plane microvortices for stationary or continuous fluid mixing

Huang, Shu‐Mei; Wang, Shou-Kai; Khoo, Hwa Seng; Tseng, Fan‐Gang

doi:10.1016/j.snb.2007.01.046

Cited by 53 publications

(24 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…4 Similar mixers were subsequently reported by others. [5][6][7] These experimental results obtained with our mixer and by others clearly indicate the applicability of AC-EOF to fluid mixing in microfluidic devices.…”

Section: Introductionsupporting

confidence: 81%

“…Moreover, the mixing index can be estimated from the concentration profile calculated from Eqs. (4) and (5). These estimations can provide guidelines for using the AC-EOF mixer in microfluidic chemical analysis, such as the labeling of analytes prior to detection, or the preparation of various concentrations of solutions from a single standard solution. )…”

Section: /2mentioning

confidence: 99%

See 1 more Smart Citation

Experimental and Theoretical Characterization of an AC Electroosmotic Micromixer

2010

View full text Add to dashboard Cite

Section: Introductionsupporting

confidence: 81%

Section: /2mentioning

confidence: 99%

Experimental and Theoretical Characterization of an AC Electroosmotic Micromixer

2010

View full text Add to dashboard Cite

“…Of late, theoretical and experimental studies on AC electrokinetics [26][27][28] have extended to AC electroosmosis (ACEO) 29,30 and AC electrothermal (ACET). 31 The mechanism of ACEO is not effective in the highconductivity fluid and unsuitable for the fluids in organs-on-a-chip platforms.…”

Section: Introductionmentioning

confidence: 99%

In-plane microvortices micromixer-based AC electrothermal for testing drug induced death of tumor cells

et al. 2016

View full text Add to dashboard Cite

Herein, we first describe a perfusion chip integrated with an AC electrothermal (ACET) micromixer to supply a uniform drug concentration to tumor cells. The inplane fluid microvortices for mixing were generated by six pairs of reconstructed novel ACET asymmetric electrodes. To enhance the mixing efficiency, the novel ACET electrodes with rotating angles of 0 , 30 , and 60 were investigated. The asymmetric electrodes with a rotating angle of 60 exhibited the highest mixing efficiency by both simulated and experimental results. The length of the mixing area is 7 mm, and the mixing efficiency is 89.12% (approximate complete mixing) at a voltage of 3 V and a frequency of 500 kHz. The applicability of our micromixer with electrodes rotating at 60 was demonstrated by the drug (tamoxifen) test of human breast cancer cells (MCF-7) for five days, which implies that our ACET inplane microvortices micromixer has great potential for the application of drug induced rapid death of tumor cells and mixing of biomaterials in organs-on-a-chip systems. Published by AIP Publishing. [http://dx

show abstract

“…Diverse particle manipulation techniques based on DEP have been reported for the past two decades [1][2][3][4][5][6][7][8][9][10][11][12][13]. More recently, ACEO and ETF have also been discovered [14][15][16] and some of their applications have been explored [17][18][19]. Strictly speaking, these are electrohydrodynamic phenomena and their major application is mixing, which is a challenging task in microchannel laminar flows and miniature biosensor platforms [20,21].…”

Section: Introductionmentioning

confidence: 99%

Dielectrophoretic particle–particle interaction under AC electrohydrodynamic flow conditions

Lee

Papazoglou

et al. 2011

Electrophoresis

View full text Add to dashboard Cite

We used the Maxwell stress tensor method to understand dielectrophoretic particle-particle interactions and applied the results to the interpretation of particle behaviors under alternating current (AC) electrohydrodynamic conditions such as AC electroosmosis (ACEO) and electrothermal flow (ETF). Distinct particle behaviors were observed under ACEO and ETF. Diverse particle-particle interactions observed in experiments such as particle clustering, particles keeping a certain distance from each other, chain and disc formation and their rotation, are explained based on the numerical simulation data. The improved understanding of particle behaviors in AC electrohydrodynamic flows presented here will enable researchers to design better particle manipulation strategies for lab-on-a-chip applications.

show abstract

AC electroosmotic generated in-plane microvortices for stationary or continuous fluid mixing

Cited by 53 publications

References 25 publications

Experimental and Theoretical Characterization of an AC Electroosmotic Micromixer

Experimental and Theoretical Characterization of an AC Electroosmotic Micromixer

In-plane microvortices micromixer-based AC electrothermal for testing drug induced death of tumor cells

Dielectrophoretic particle–particle interaction under AC electrohydrodynamic flow conditions

Contact Info

Product

Resources

About