Abuse and Misuse of Selected Dietary Supplements Among Adolescents: a Look at Poison Center Data

Biggs, Jessica M; Morgan, Jill A.; Lardieri, Allison; Kishk, Omayma A.

doi:10.5863/1551-6776-22.6.385

Cited by 11 publications

(10 citation statements)

References 50 publications

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“…Bird et al, 2016), adverse effects are emerging for uncontrolled PAES (e.g. Metzl et al, 2001;Biggs et al, 2017). More importantly, PAES use is increasing public policy concerns, as the use of unconrolled PAES (e.g.…”

Section: Discussionmentioning

confidence: 99%

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The Implementation and Evaluation of a Media Literacy Intervention About PAES Use in Sport Science Students

et al. 2020

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With respect to both competitive and amateur/fitness sports, media may strongly influence young people's opinions and behaviors concerning the use of PAES (Performance and Appearance Enhancing Substances). The present investigation addressed this topic by focusing on sport sciences students' beliefs concerning the possible role of media related to the implementation and evaluation of a PAES-focus media literacy intervention conducted with sport science students. This study relied on a sample of 521 students (attrition rate 10.3%) (45.1% female, mean age = 22.6, SD = 2.20), which provided baseline data on students' levels of media literacy concerning the use of PAES (i.e. "descriptive sample"), and a sample of 248 students, who participated in and provided data on the media literacy intervention. This latter sample included a group of 128 students (44.5% female, mean age = 23.03, SD = 3.76) who actively participated in the intervention (i.e. "intervention group"), and a group of 120 students who did not (i.e. "control group", 53.3% female, mean age = 22.25, SD = 2.47). All students filled out media literacy questionnaires targeting students' awareness of media influence, their views about the realism of media content, their sense of confidence in dealing with media messages, and their positive attitudes toward PAES use. Analyses of questionnaire data showed that students are relatively aware of media influence on people's views and behaviors with respect to PAES use. At the same time, students also believed that young people do not consider media as "realistic sources" of information; nonetheless, they also did not consider themselves entirely capable of dealing effectively with media messages. With respect to the intervention, students overall appreciated and greatly welcomed the educational program on media literacy, and the analyses of intervention data across intervention and control groups showed that key media literacy variables changed over time, attesting to the overall effectiveness of the intervention.

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Section: Discussionmentioning

confidence: 99%

“…As in the case of "controlled" PAES, this increase has raised some concerns with respect to their long-term health consequences (e.g. Metzl et al, 2001;Biggs et al, 2017).…”

Section: Introduction the Use Of Substances Guided By Performance Andmentioning

confidence: 99%

The Implementation and Evaluation of a Media Literacy Intervention About PAES Use in Sport Science Students

et al. 2020

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“…The use of herbal nutraceuticals including G. cambogia is higher in females when compared to males. 124 Hence, to spread awareness, scientifically reported adverse effects possibly linked with the use of G. cambogia are compiled below.…”

Section: Resultsmentioning

confidence: 99%

Awareness on the possible adverse effects of Garcinia cambogia: A scientific approach

Zothantluanga

Lalnunpuii

Bhat

et al. 2020

Sci Vis

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The modern popular ideology is that plant-based products do not have adverse effects. Hence, people are fond of using herbal products of their choice to treat their own ailments or anyone else. As majority of the population are not aware of herbal toxicity concept, the use of formulated single or combined medicinal and/or nutritional plant extracts or isolated compounds to treat chronic diseases are increasingly popular due to the widespread concerns regarding the adverse effects of pharmaceutical drugs. Awareness from the scientific community to bring society to its senses regarding the safety issue of a herbal product is rare. Garcinia gummi-gutta (more popularly known by the synonym Garcinia cambogia in commercial preparations), belonging to the family of Clusiaceae (alt. Guttiferae) is a popularly consumed weight-loss nutraceutical. This review aims to highlight the possible adverse effects of G. cambogia. For the said purpose, 147 articles were collected from PubMed, Web of Science and Google scholar. Literature review revealed a plethora of beneficial actions. Investigational outcomes and clinical evidences hint the possible adverse effects likely to be linked with the use of G. cambogia. However, the use of G. cambogia as an anti-obesity agent is advisable as long as the therapeutic value outweighs the adverse effect.

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“…The EMA determined in its guidelines the adult dosage is a total 900 mg/day (three-times 300 mg/day) for the treatment of depression (5). Unfortunately, it has been reported that it can be abused among adolescents who believe it can make them feel good (8), in this case, its limited upper dose has not been established due to its non-prescription use. Depression can affect people of any age and disturb fertility, and any woman could be exposed to H. perforatum , assuming that it is safe, either before being pregnant and even while pregnant.…”

Section: Discussionmentioning

confidence: 99%

Detrimental effect of Hypericum perforatum on ovarian functions

Demirci¹,

Kahyaoğlu²,

Atakul³

et al. 2019

J Turkish German Gynecol Assoc

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Objective: Hypericum perforatum is widely used for depression and distress treatment as an over-the-counter plant at any age. This study investigated the safety of H. perforatum on ovarian function and infertility. Material and Methods: H. perforatum was given to rats in two different dosages (100 and 300 mg/kg/day) with drinking water for four weeks. Half of the treatment groups were sacrificed at the end of the four-week intervention, the remainder was sacrificed after an additional four-week waiting period to see if there was reversibility. At the end of the experiment, blood samples and both ovarian tissues were obtained under anesthesia with ketamine and xylazine (50 mg/kg and 5 mg/kg, respectively). Results: Although primordial follicle numbers were not affected with a dose of 100 mg/kg, they were significantly decreased (28.6%) when the dose was tripled. Primary follicle numbers stayed the same, but secondary and tertiary follicles numbers were significantly dose-dependently decreased, and remained significantly low four weeks after the intervention. Anti-mullerian hormone (AMH) levels were not significantly different between the groups. Conclusion: H. perforatum treatment did not change serum levels of AMH because the primary follicle number did not decrease. However, the other follicle counts decreased in a dose-dependent manner and full recovery was not regained after four weeks. The detrimental effect of H. perforatum on primordial follicles should be taken into consideration because any woman using H. perforatum could also experience ovarian failure.

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Abuse and Misuse of Selected Dietary Supplements Among Adolescents: a Look at Poison Center Data

Abstract: Abuse and misuse of these dietary supplements was uncommon, and outcomes were mild. Further research should be performed to determine use and outcomes of abuse/misuse of other dietary supplements in this population.

Cited by 11 publications

References 50 publications

The Implementation and Evaluation of a Media Literacy Intervention About PAES Use in Sport Science Students

The Implementation and Evaluation of a Media Literacy Intervention About PAES Use in Sport Science Students

Awareness on the possible adverse effects of Garcinia cambogia: A scientific approach

Detrimental effect of Hypericum perforatum on ovarian functions

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