Abstract 335: Ubiquitin Specific Peptidase 37promotes Osteosarcoma oncogenesis by interacting with PCNA and impacting constitutive replication fork movement.
Abstract:Osteosarcoma is the heterogeneous primary malignancy of bone which is most commonly found among children and adolescents. Recent data related to treatment of osteosarcoma indicates the lack information about the progression of the disease. Osteosarcoma has been a challenge for the oncologist because even after surgical removal of primary tumors many patients go on to develop pulmonary metastasis. Protein deubiquitination controls many intracellular processes, including cell cycle progression, transcriptional a… Show more
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