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The p53 is the master regulator of the cell known for regulating a large array of cellular processes. Inactivation of p53 by missense mutations is one of the leading causes of cancer. Some of these mutations endow p53 with selective oncogenic functions to promote tumor progression. Due to the vast array of mutations found in p53, the experimental studies showing the role of different mutant p53 as an oncogene are also expanding. In this review, we discuss the oncogenic roles of different p53 mutants at the cellular level identified by multi-omics tools. We discuss some of the therapeutic studies to tackle p53 mutants and their downstream targets identified by omics. We also highlight the future prospective and scope of further studies of downstream p53 targets by omics.

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Sixth sense' is a way of opening up to the vast world which cannot be identified by five senses. Mr. Steve Mann in 1990 started working on this idea which led to the innovation of 'Sixth sense technology' using a Telepointer, a wearable device for the experience of visuals on real world objects. His wok was then carried on by a younger lad, Pranav Mistry.Sixth sense device is based on gesture interactions and its interface, a kind of device which doesn't need to carry any big attribute like a camera or watch. Six sense technology is a new & interesting stream of technology, which can be the most approachable as it is all about interacting with the digiworld directly. The device uses mirror, camera, pocket projector, smart phone & color markers to identify any object or some view and then it imparts it over the real world.