Absorption spectroscopy setup for determination of whole human blood and blood–derived materials spectral characteristics

Wróbel, Maciej S.; Gnyba, Marcin; Milewska, D.; Mitura, Katarzyna; Karpienko, Katarzyna

doi:10.1117/12.2201132

Cited by 1 publication

(1 citation statement)

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“…Absorption spectra were recorded for samples of the human blood and blood with ND particles, to assess the induced changes. For this purpose, a custom-built spectrometer set-up was used, as described in detail in our previous publications [ 47 ]. The set-up consisted of a compact spectrometer (Flame, Ocean Optics Inc., Dunedin, FL, USA) with a 190–1100 nm range, tungsten-halogen light source (BP101, B&W Tek, Newark, DE, USA), optical fibers, and a sample holder.…”

Section: Methodsmentioning

confidence: 99%

Haemocompatibility of Modified Nanodiamonds

et al. 2017

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This study reports the interactions of modified nanodiamond particles in vitro with human blood. Modifications performed on the nanodiamond particles include oxygenation with a chemical method and hydrogenation upon chemical vapor deposition (CVD) plasma treatment. Such nanodiamonds were later incubated in whole human blood for different time intervals, ranging from 5 min to 5 h. The morphology of red blood cells was assessed along with spectral measurements and determination of haemolysis. The results showed that no more than 3% of cells were affected by the nanodiamonds. Specific modifications of the nanodiamonds give us the possibility to obtain nanoparticles which are biocompatible with human blood. They can form a basis for the development of nanoscale biomarkers and parts of sensing systems and devices useful in biomedical environments.

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Section: Methodsmentioning

confidence: 99%