2022
DOI: 10.1007/s10549-022-06748-4
|View full text |Cite
|
Sign up to set email alerts
|

Absolute lymphocyte count decreases with disease progression and is a potential prognostic marker for metastatic breast cancer

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
4
1

Citation Types

0
5
0

Year Published

2023
2023
2024
2024

Publication Types

Select...
6
1

Relationship

0
7

Authors

Journals

citations
Cited by 8 publications
(5 citation statements)
references
References 25 publications
0
5
0
Order By: Relevance
“…In breast cancer, the absolute lymphocyte count gradually decreases with the progression of metastatic breast cancer. Monitoring changes in lymphocyte count in peripheral blood is a potential indicator for predicting recurrence [24]. In addition, peripheral blood lymphocyte counts are signi cantly positively correlated with Tumor-in ltrating lymphocytes in ltrating tumor tissue locally.…”
Section: Discussionmentioning
confidence: 99%
“…In breast cancer, the absolute lymphocyte count gradually decreases with the progression of metastatic breast cancer. Monitoring changes in lymphocyte count in peripheral blood is a potential indicator for predicting recurrence [24]. In addition, peripheral blood lymphocyte counts are signi cantly positively correlated with Tumor-in ltrating lymphocytes in ltrating tumor tissue locally.…”
Section: Discussionmentioning
confidence: 99%
“… 15 Lymphocyte count decrease is a sign of poor prognosis for cancer. 16 , 17 Low hemoglobin levels reflect tumor hypoxia, which can reduce the efficacy of radiotherapy. 18 Platelet is associated with metastasis, which can defend cancer cells from immune assault.…”
Section: Introductionmentioning
confidence: 99%
“…ALC can provide a surrogate measure of the host's inflammatory and immune responses given the critical role of lymphocytes in the tumor‐related immune response 5 . A number of studies have shown an association between lymphopenia and poor prognosis in cancers such as sarcoma, breast cancer, renal cancer, and gastric cancer 4,6–9 …”
Section: Introductionmentioning
confidence: 99%
“…5 A number of studies have shown an association between lymphopenia and poor prognosis in cancers such as sarcoma, breast cancer, renal cancer, and gastric cancer. 4,[6][7][8][9] However, the existing data on the reliability of ALC as a prognostic biomarker is mixed, with some studies showing inconsistent results regarding pretreatment lymphocyte counts. For instance, Punjabi et al showed no significant correlation between pretreatment ALC and survival outcomes in nonsmall cell lung cancer, although there was an association between postradiotherapy ALC and survival outcomes.…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation