“…Although further direct evidence is needed, our results are compatible with the hypothesis that oxidative stress response plays a role in sports anemia. 6,10,12 Exercise-induced hemolysis is a widely observed phenomenon during long-distance running. An athlete's typical blood profile includes a decrease of haptoglobin and an increase of plasma Hb levels.…”
Section: Discussionmentioning
confidence: 99%
“…5,8 Athletes can also lose considerable quantities of iron due to bleeding from the gastrointestinal and urinary tracts. 9,10 It has been suggested that the lasting high levels of erythropoietin (EPO) may promote an increase in red cell mass to maintain tissue oxygen levels after a marathon run. 11,12 To our knowledge, there has been no published report that describes the overall hematological, urinary, and fecal changes of the anemia phenomenon in Asian male ultramarathoners after a 100-km (62.5-mile) ultramarathon event.…”
Running a 100-km ultramarathon will induce substantial sports anemia, and oxidative stress response, hemolysis, hematuria, and gastrointestinal bleeding are typical factors that contribute to its onset.
“…Although further direct evidence is needed, our results are compatible with the hypothesis that oxidative stress response plays a role in sports anemia. 6,10,12 Exercise-induced hemolysis is a widely observed phenomenon during long-distance running. An athlete's typical blood profile includes a decrease of haptoglobin and an increase of plasma Hb levels.…”
Section: Discussionmentioning
confidence: 99%
“…5,8 Athletes can also lose considerable quantities of iron due to bleeding from the gastrointestinal and urinary tracts. 9,10 It has been suggested that the lasting high levels of erythropoietin (EPO) may promote an increase in red cell mass to maintain tissue oxygen levels after a marathon run. 11,12 To our knowledge, there has been no published report that describes the overall hematological, urinary, and fecal changes of the anemia phenomenon in Asian male ultramarathoners after a 100-km (62.5-mile) ultramarathon event.…”
Running a 100-km ultramarathon will induce substantial sports anemia, and oxidative stress response, hemolysis, hematuria, and gastrointestinal bleeding are typical factors that contribute to its onset.
“…The latter would be expected from any novel biomarker proposed today for clinical application as diagnostic or prognostic marker. In view of these points it may be timely to address the question if a more differentiating perspective on anaemia in normal populations (primary prevention), specific populations such as athletes [12] or elderly subjects [13], and in patients of varying conditions may be more appropriate, and if disease specific cut-off levels would provide even stronger information.…”
“…5 Around 10-15% of athletes with iron deficiency do have a mild form of anaemia. [3][4][5] Particularly if other contributory factors are involved (for example, dietary restrictions and menstrual bleeding), anaemia can be more severe, as described in the above cases. Several mechanisms are generally accepted to cause iron loss during exercise:…”
Section: Casementioning
confidence: 97%
“…2 Iron deficiency is common in athletes involved in endurance sports. [3][4][5] In female marathon runners, the prevalence is as high as 28% (compared to 11% in the general female population). 5 Around 10-15% of athletes with iron deficiency do have a mild form of anaemia.…”
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