Absence of Peripheral Eosinophilia on Initial Clinical Presentation Does Not Rule Out the Diagnosis of Acute Eosinophilic Pneumonia

Meropenem: A possible new culprit in eosinophilic lung diseases

“…Peripheral eosinophilia can either be present or absent. [ 8 ] Lung biopsy is often unnecessary to establish the diagnosis in drug-induced EP, it is however performed when the causative agent is uncertain or to rule out other disease entities that could explain the clinical picture. [ 2 ]…”

Eosinophilic pneumonia: remember topical drugs as a potential etiology

“…Although there have been reports of peripheral eosinophilia in patients with EP, it is not always observed in such patients, especially those with acute EP. 6 In such patients, BAL or biopsy can provide insight as to the likelihood of peripheral eosinophilia (eosinophil levels above 25% in differential cell counts in BAL fluid).…”

Eosinophilia in Pulmonary Disorders

“…The hallmark is a blood eosinophilia (bacterial and viral pneumonias are almost invariably associated with an eosinopenia), although the blood eosinophil count can be transiently normal on presentation, presumably due to the rapid migration of eosinophils into the lung. 49 Both the blood and lung eosinophilia start to resolve within 48 hours with high-dose systemic corticosteroids. EP can unusually be associated with endomyocardial fibrosis, and cardiac MRI should be performed.…”