An in-depth knowledge of the anatomy and biomechanics of the flexor tendon system is essential to every stage of the management of flexor tendon injuries from diagnosis, surgery, correct assessment of complications through to secondary surgery. It must be remembered that this is a carefully balanced system with the function of any particular muscle not depend ing only on its origin and insertion, but the complex interplay between the system of pulleys in the hand and the balancing forces of all the muscles acting across the intervening joints. For example the effect of flexor digitorum profundus (FDP) acting alone would be to act purely at the distal interphalangeal (DIP) joint until this was fully flexed before acting at the proximal interphalangeal (PIP) joint in a similar manner, followed by the metacarpophalangeal (MCP) joint and lastly the wrist. However in normal function, such as grasping an object, the action of FDP will always be accompanied by balancing tensions in other muscles, and moderated by the pulley system to produce the desired functional outcome. For example, in grasping an object the wrist is stabilized and the joints of the finger are simulta neously flexed around the object. Figure 51.1 shows the structure of flexor digitorum superfi cialis (FDS) as it divides and rejoins to become deep to FDP just before its insertion. This illustrates the complexity of just one element of the interplay between anatomy and function.The wrist flexors and FDS are part of the superficial flexor muscle mass in the forearm arising from the common flexor origin. Both of the wrist flexors have pulley systems close to their insertions that redirect the vector of force and thereby increase the efficiency of their action. The flexor carpi radialis (FCR) is redirected by the scaphoid before being inserted into the bases of the second and third metacarpals and the flexor carpi ulnaris (FCU) is redirected by the pisiform before its insertion into the base of the fifth metacarpal. The FDS muscle also has an origin from the radius, and provides independent control of pull for the FDS tendon to each digit, with the exception that the action on the little and ring is sometimes conjoined (see under Clinical examination below). The function of FDS is partly to assist with power grip, but more importantly provides individual finger flexion as required in manipulation of objects in the hand and in fine motor skills. As the FDS is inserted into the base of the middle phalanx, it acts mainly at the PIP joint, but also crosses the wrist and MCP joint, where the magnitude of its effect is determined by the balance of tension in the other muscles act ing at these sites, such as the wrist flexors and extensors, the long finger extensors, and, importantly, the interossei and lumbricals.The deep flexor muscle mass consists of flexor pollicis longus (FPL) arising from the palmar surface of the body of the radius, and the FDP arising from the ulna. FPL is the only flexor of the thumb and provides the strongest pull of all the flexors to...