Abortions in First Trimester Pregnancy, Management, Treatment

Tsikouras, Panagiotis; Deftereou, Theodora; Anthoulaki, Xanthoula; Bothou, Anastasia; Chalkidou, Anna; Gaitatzi, Fotini; Tsirkas, Ioannis; Bourazan, Arsou Chalil; Bampageorgaka, Eirini; Stanulov, George; Chatzimichael, Elefterios; Michalopoulos, Spyridon; Petsidis, Panagiotis; Iatrakis, Georgios; Zervoudis, Stefanos; Lambropoulou, María; Rath, Werner; Γαλάζιος, Γεώργιος

doi:10.5772/intechopen.86194

Cited by 4 publications

(3 citation statements)

References 101 publications

(332 reference statements)

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“…Women who have had one miscarriage make up 10.8% of the population (10.3-11.4%), two miscarriages make up 1.9% of the population (1.8-2.1%), and three or more losses make up 0.7% of the population (0.5-0.8%) (1). Spontaneous abortion has emerged as a serious global reproductive health concern, with negative consequences for physical and mental health as well as increased economic strain (7,8). The incidence of spontaneous abortion in developed nations such as the United States of America is approximately 15.7%, and in China, it is 5%; in India approximately 4.7% of pregnancies end up as spontaneous abortion (SAB).…”

Section: Introductionmentioning

confidence: 99%

Predictors of Spontaneous Abortion Among Women Attending Referral and Specialized Public Hospitals of East Ethiopia, A Case-Control Study

Amsalu,

Kasahun,

Hailu

et al. 2024

Preprint

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Background Spontaneous abortion is one of the most common complications of early pregnancy, occurring in 15–20% of pregnant women. Every year, an estimated 23 million miscarriages occur worldwide, resulting in 44 pregnancy losses every minute. Consistent findings show that spontaneous abortion has a negative impact on current and consecutive pregnancies. It also has an enormous economic impact. When all of these factors are combined with the idiopathic nature of the problem, identifying predictors of spontaneous abortion will have a significant impact on preventing the problem. However, no studies have been conducted in Ethiopia on this topic. Therefore, this study aims to assess the predictors of spontaneous abortion among women attending referral and specialized public hospitals in Eastern Ethiopia. Methods An institutional-based unmatched case-control study design was used. Three hundred seventy-one (371) cases and three hundred seventy-one (371) controls were studied. The data were collected by using an interviewer-administered structured questionnaire. The collected data were entered into Epi data version 4.6 and then exported to SPSS window version 25 for analysis. Bivariate and multivariate analyses were used to determine the associations between each independent variable and the outcome variable. All the variables with a P value ≤ 0.25 in the bivariate analysis were included in the final model of multivariable analysis to control for possible confounders. A P value < 0.05 was considered to indicate a statistically significant association. Result The following predictors were significantly associated with spontaneous abortion, intended pregnancy [AOR = 0.443, 95% CI: (0.279, 0.703)], folate intake during the current pregnancy [AOR = 0.067, 95% CI: (0.042, 0.106)], coffee consumption [AOR = 3.699, 95% CI: (2.341, 5.846)], stressful life events [AOR = 7.55, 95% CI: (3.932, 14.496)], and history of spontaneous abortion [AOR = 8.86, 95% CI: (3.197, 24.604)]. Conclusion This study provides evidence that several predictors are independently associated with spontaneous abortion. Importantly, many of these factors can be modified or prevented through appropriate awareness and education among reproductive-age women. By addressing these risk factors, the incidence of spontaneous abortion can be reduced.

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Section: Introductionmentioning

confidence: 99%

Predictors of Spontaneous Abortion Among Women Attending Referral and Specialized Public Hospitals of East Ethiopia, A Case-Control Study

Amsalu,

Kasahun,

Hailu

et al. 2024

Preprint

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“…A first-trimester miscarriage occurs before the fetus is viable, 15.3% of diagnosed pregnancies experience miscarriages, one of the most common early pregnancy complications (1). Over 80% of miscarriages occur in the first 12 weeks (2). Miscarriages have become a global reproductive health issue, affecting physical, mental, and economic wellbeing (3).…”

Section: Introductionmentioning

confidence: 99%

Vaginal Microbiota Profile in first-trimester miscarriages cases

Saman Rafeeq Abdulla,

Sarmad Raheem Kareem,

Ayad H. Hasan

2023

Cell Mol Biol (Noisy-le-grand)

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Due to its rising prevalence, first-trimester miscarriage is getting more attention. Abortion etiology and pathology, especially in non-pathological cases, are unknown. In this study, 435 vaginal swabs were collected from aborted women in Maternity Teaching Hospitals in Erbil and Shahid Dr. Khalid Hospital in Koya. We characterized the vaginal microbiota diversity and composition in first-trimester abortion and investigated the association between bacterial vaginosis and abortion before 12 weeks. Cultural, morphological, and biochemical characteristics for each bacterial genus were discovered, and VITEK-2 system was used to identify isolated bacteria. Samples from each type of bacteria were selected for sequencing utilizing 16 rRNA genes examining V4-V8 region for bacterial profiles. Bacterial vaginitis was found in 412 (94.7%) first-trimester miscarriages. Six Gram-positive and four Gram-negative bacteria were found in these 412 samples. Microorganism distribution varied Gram-positive bacteria Staphylococcus aureus (86) 20.87%, Enterococcus faecalis (31) 7.52%, Gardnerella vaginalis (24) 5.83%, Streptococcus agalactia (21) 5.1%, Lactobacillus equicursoris (14) 3.4% and Staphylococcus haemolyticus (12) 2.91%. Gram-negative bacteria including E. coli (107) 25.97%, Klebsiella pneumonia (76) 18.45%, Pseudomonas aeruginosa (29) 7.04% and Proteus mirabilis (12) 2.91%. Staphylococcus aureus had the highest rate of isolation at (86) 20.87%, while Lactobacillus equicursoris had the lowest rate at (14) 3.4%. Overall, the rate of isolation for Gram-negative bacteria (224) was 54.4%, while the rate for Gram-positive bacteria (188) was 45.6%.

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“…As one of the most common complications to occur in early pregnancy, the incidence of SA has reached 15.3% of all recognized pregnancies ( 1 ). Moreover, >80% of SA cases occur in the first 12 weeks of gestation ( 2 ). SA has therefore become a definite global reproductive health issue, leading to adverse effects on physical and mental health and increasing economic pressure ( 3 , 4 ).…”

Section: Introductionmentioning

confidence: 99%