ABLs and TMKs are co-receptors for extracellular auxin

Yu, Yongqiang; Tang, Wenxin; Lin, Wenwei; Li, Wei; Zhou, Xiang; Li, Ying; Chen, Rong; Zheng, Rui; Qin, Guochen; Cao, Wenhan; Pérez-Henríquez, Patricio; Huang, Rongfeng; Ma, Jun; Qiu, Qiqi; Xu, Ziwei; Zou, Ailing; Lin, Juncheng; Jiang, Liwen; Xu, Tongda; Yang, Zhenbiao

doi:10.1016/j.cell.2023.10.017

Cited by 30 publications

(19 citation statements)

References 78 publications

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“…Although no clear ortholog is present in Marchantia, 91 ABP1 is a member of the large Cupin family, and other members of this family in Arabidopsis also appear to function as auxin receptors. 92 This raises the interesting possibility that the broader Cupin family, represented in all domains of life, 93 may act as auxin receptors for fast responses, including those mediated by RAF.…”

Section: Discussionmentioning

confidence: 99%

RAF-like protein kinases mediate a deeply conserved, rapid auxin response

Kuhn,

Roosjen,

Mutte

et al. 2024

Cell

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Section: Discussionmentioning

confidence: 99%

RAF-like protein kinases mediate a deeply conserved, rapid auxin response

Kuhn,

Roosjen,

Mutte

et al. 2024

Cell

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“…The identification of genes required for plant hormone biosynthesis and action resulted largely from the use of genetic approaches applied to the model eudicot species Arabidopsis ( Arabidopsis thaliana ). This branch of research greatly advanced our understanding of how “linear” phytohormone-response pathways function at the molecular level, including the discovery of ethylene as the first gaseous signaling molecule ( Kende 1998 ), the elucidation of mechanisms to perceive steroids and auxins at the cell surface ( He et al 2000 ; Yu et al 2023 ), and the paradigm that some hormones act as molecular glue to promote the reorganization of transcription complexes ( Dharmasiri et al 2003 ; Tan et al 2007 ; Sheard et al 2010 ). A deep mechanistic understanding of phytohormone-response pathways has also provided a foundation on which to explore more complex questions, such as the evolutionary origins of chemical communication in plants, cross-regulation between phytohormone-response pathways, the ecological relevance of phytohormones, and strategies to engineer economically important plant traits.…”

Section: Phytohormones As Regulatory Metabolitesmentioning

confidence: 99%

Phytohormones in a universe of regulatory metabolites: lessons from jasmonate

Gasperini,

Howe

2024

Plant Physiology

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Small-molecule phytohormones exert control over plant growth, development, and stress responses by coordinating the patterns of gene expression within and between cells. Increasing evidence indicates that currently recognized plant hormones are part of a larger group of regulatory metabolites that have acquired signaling properties during the evolution of land plants. This rich assortment of chemical signals reflects the tremendous diversity of plant secondary metabolism, which offers evolutionary solutions to the daunting challenges of sessility and other unique aspects of plant biology. A major gap in our current understanding of plant regulatory metabolites is the lack of insight into the direct targets of these compounds. Here, we illustrate the blurred distinction between classical phytohormones and other bioactive metabolites by highlighting the major scientific advances that transformed the view of jasmonate from an interesting floral scent to a potent transcriptional regulator. Lessons from jasmonate research generally apply to other phytohormones and thus may help provide a broad understanding of regulatory metabolite-protein interactions. In providing a framework that links small-molecule diversity to transcriptional plasticity, we hope to stimulate future research to explore the evolution, functions, and mechanisms of perception of a broad range of plant regulatory metabolites.

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“…Auxin can also be perceived in cells by the apoplastic receptor ABP1 (AUXIN BINDING PROTEIN1) and its homologues ABL1 and 2 (ABP1 LIKE1 and 2). Those proteins bind auxin together with the Transmembrane Receptor Kinases (TMKs), inducing an ultrafast phospho-response ( Friml et al, 2022 ; Yu et al, 2023 ). TMK proteins phosphorylate also plasma membrane H + -ATPases, important regulators of growth ( Pacifici et al, 2018 ; Lin et al, 2021 ), and ABA INSENSITIVE 1 and 2 (ABI1 and ABI2), negative regulators of Abscisic Acid response ( Yang et al, 2021 ).…”

Section: Auxin Biosynthesis Transport and Signallingmentioning

confidence: 99%

Role of transcriptional regulation in auxin-mediated response to abiotic stresses

Marzi,

Brunetti,

Saini

et al. 2024

Front. Genet.

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Global climate change (GCC) is posing a serious threat to organisms, particularly plants, which are sessile. Drought, salinity, and the accumulation of heavy metals alter soil composition and have detrimental effects on crops and wild plants. The hormone auxin plays a pivotal role in the response to stress conditions through the fine regulation of plant growth. Hence, rapid, tight, and coordinated regulation of its concentration is achieved by auxin modulation at multiple levels. Beyond the structural enzymes involved in auxin biosynthesis, transport, and signal transduction, transcription factors (TFs) can finely and rapidly drive auxin response in specific tissues. Auxin Response Factors (ARFs) such as the ARF4, 7, 8, 19 and many other TF families, such as WRKY and MADS, have been identified to play a role in modulating various auxin-mediated responses in recent times. Here, we review the most relevant and recent literature on TFs associated with the regulation of the biosynthetic, transport, and signalling auxin pathways and miRNA-related feedback loops in response to major abiotic stresses. Knowledge of the specific role of TFs may be of utmost importance in counteracting the effects of GCC on future agriculture and may pave the way for increased plant resilience.

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ABLs and TMKs are co-receptors for extracellular auxin

Cited by 30 publications

References 78 publications

RAF-like protein kinases mediate a deeply conserved, rapid auxin response

RAF-like protein kinases mediate a deeply conserved, rapid auxin response

Phytohormones in a universe of regulatory metabolites: lessons from jasmonate

Role of transcriptional regulation in auxin-mediated response to abiotic stresses

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