Ability of a novel blue laser imaging system for the diagnosis of colorectal polyps

Yoshida, Naohisa; Yagi, Nobuaki; Inada, Yutaka; Kugai, Munehiro; Okayama, Tetsuya; Kamada, Kazuhiro; Katada, Kazuhiro; Uchiyama, Kazuhiko; Ishikawa, Takeshi; Handa, Osamu; Takagi, Tomohisa; Konishi, Hideyuki; Kokura, Satoshi; Yanagisawa, Akio; Naito, Yuji

doi:10.1111/den.12127

Cited by 101 publications

(93 citation statements)

References 29 publications

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“…The combination of strong 410-nm laser light, weak 450-nm laser light, and fluorescent light enables blue laser imaging (BLI) via narrow-band light observation. Magnifying endoscopy with BLI (M-BLI) is useful for evaluating mucosal surface information such as surface blood vessel and structure patterns [13][14][15][16].…”

Section: Introductionmentioning

confidence: 99%

Diagnostic ability of magnifying endoscopy with blue laser imaging for early gastric cancer: a prospective study

et al. 2016

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Background Blue laser imaging (BLI) is a new image-enhanced endoscopy technique that utilizes a laser light source developed for narrow-band light observation. The aim of this study was to evaluate the usefulness of BLI for the diagnosis of early gastric cancer. Methods This single center prospective study analyzed 530 patients. The patients were examined with both conventional endoscopy with white-light imaging (C-WLI) and magnifying endoscopy with BLI (M-BLI) at Kyoto Prefectural University of Medicine between November 2012 and March 2015. The diagnostic criteria for gastric cancer using M-BLI included an irregular microvascular pattern and/or irregular microsurface pattern, with a demarcation line according to the vessel plus surface classification system. Biopsies of the lesions were taken after C-WLI and M-BLI observation. The primary end point of this study was to compare the diagnostic performance between C-WLI and M-BLI. Results We analyzed 127 detected lesions (32 cancers and 95 non-cancers). The accuracy, sensitivity, and specificity of M-BLI diagnoses were 92.1, 93.8, and 91.6 %, respectively. On the other hand, the accuracy, sensitivity, and specificity of C-WLI diagnoses were 71.7, 46.9, and 80.0 %, respectively.Conclusions M-BLI had improved diagnostic performance for early gastric cancer compared with C-WLI. These results suggested that the diagnostic effectiveness of M-BLI is similar to that of magnifying endoscopy with narrow-band imaging (M-NBI).

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Section: Introductionmentioning

confidence: 99%

Diagnostic ability of magnifying endoscopy with blue laser imaging for early gastric cancer: a prospective study

et al. 2016

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“…At first, we perform a pre-check colonoscopy before ESD for the accurate diagnosis ( Figure 2A). Regularly, we adopt magnifying observation using narrow band imaging, blue laser imaging, and chromoendoscopy ( Figure 2B) (15)(16)(17)(18)(19). We also determine the status of manipulation about endoscope.…”

Section: Our Overall Esd Results and Principles Of Esdmentioning

confidence: 99%

Tips for safety in endoscopic submucosal dissection for colorectal tumors

et al. 2017

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In Japan, endoscopic submucosal dissection (ESD) becomes one of standard therapies for large colorectal tumors. Recently, the efficacy of ESD has been reported all over the world. However, it is still difficult even for Japanese experts in some situations. Right-sided location, large tumor size, high degree of fibrosis, difficult manipulation is related with the difficulty. However, improvements on ESD devices, suitable strategies, and increase of operators' experiences enable us to solve these problems. In this chapter, we introduce recent topics about various difficult factors of colorectal ESD and the tips such as strategy, devices, injection, and traction method [Pocketcreation method (PCM) etc.].

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“…[36][37][38][39] Both techniques exploit narrow-band blue light to enhance the increase in abnormal microvessels in the superficial mucosa, which is one of the characteristic morphological features of cancerous lesions. The technique of StO 2 imaging described in this work, however, does not focus on enhancing such morphological features of the tissue, but aims at realizing a new realm of endoscopic functional imaging through visualizing tissue oxygenation.…”

Section: Discussionmentioning

confidence: 99%

Optical imaging of hemoglobin oxygen saturation using a small number of spectral images for endoscopic application

Saito

Yamaguchi

2015

J. Biomed. Opt

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Abstract. Tissue hypoxia is associated with tumor and inflammatory diseases, and detection of hypoxia is potentially useful for their detailed diagnosis. An endoscope system that can optically observe hemoglobin oxygen saturation (StO 2 ) would enable minimally invasive, real-time detection of lesion hypoxia in vivo. Currently, point measurement of tissue StO 2 via endoscopy is possible using the commercial fiber-optic oximeter T-Stat, which is based on visible light spectroscopy at many wavelengths. For clinical use, however, imaging of StO 2 is desirable to assess the distribution of tissue oxygenation around a lesion. Here, we describe our StO 2 imaging technique based on a small number of wavelength ranges in the visible range. By assuming a homogeneous tissue, we demonstrated that tissue StO 2 can be obtained independently from the scattering property and blood concentration of tissue using four spectral bands. We developed a prototype endoscope system and used it to observe tissue-simulating phantoms. The StO 2 (%) values obtained using our technique agreed with those from the T-Stat within 10%. We also showed that tissue StO 2 can be derived using three spectral band if the scattering property is fixed at preliminarily measured values.

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Ability of a novel blue laser imaging system for the diagnosis of colorectal polyps

Abstract: BLI was useful for the diagnosis of colorectal polyps.

Cited by 101 publications

References 29 publications

Diagnostic ability of magnifying endoscopy with blue laser imaging for early gastric cancer: a prospective study

Diagnostic ability of magnifying endoscopy with blue laser imaging for early gastric cancer: a prospective study

Tips for safety in endoscopic submucosal dissection for colorectal tumors

Optical imaging of hemoglobin oxygen saturation using a small number of spectral images for endoscopic application

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