Abdominal Presentation of COVID-19

Hellinger, Jeffrey C.; Sirous, R.; Hellinger, R. L.; Krauthamer, Alan V.

doi:10.37549/ar2650

Cited by 7 publications

(2 citation statements)

References 6 publications

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“…Digital Subtraction Angiography can confirm the active bleeding seen as a "contrast blush", detect the responsible branch and provide occlusion via selective embolization. Those findings are in accordance with reports of bowel pneumatosis as a thrombotic event outcome [49], while many case reports and large case series demonstrate major abdominal-both arterial and venous-thrombosis in COVID-19 patients. In fact, many patients suffer from thrombotic occlusion despite prophylaxis or even the full-dose anticoagulation therapy supporting evidence of COVID-19 direct endothelial injury [50].…”

Section: Bleeding Manifestationssupporting

confidence: 92%

Gastrointestinal Imaging Findings in the Era of COVID-19: A Pictorial Review

Mavropoulou,

Psoma,

Papachristodoulou

et al. 2023

Medicina

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The potentially fatal COVID-19 pandemic has been associated with a largespectrum of clinical presentations. Beyond the classical pulmonary manifestations, gastrointestinal tract-related symptoms suchas nausea, diarrhea, abdominal distention and pain have been observed in patients, as a consequence of the binding of SARS-CoV-19 to Angiotensin-converting Enzyme 2 (ACE2) receptors in the gastrointestinal (GI) tract. The early recognition ofspecific imaging features, including hepatobiliary involvement, pancreatic involvement, development of solid organ infarcts, ischemic bowel changes and vascular occlusion, plays a key role through the course of the disease. Also, suspicious symptoms, especially in critically ill patients with clinical and biochemical markers of hypovolemia, necessitate timely imaging for bleeding complications. The aim of this pictorial review is to illustrate the spectrum of the GIimaging findings in patients with COVID-19. Awareness of diagnostic imaging hallmarks is crucial to optimize the management of these patients.

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Section: Bleeding Manifestationssupporting

confidence: 92%

Gastrointestinal Imaging Findings in the Era of COVID-19: A Pictorial Review

Mavropoulou,

Psoma,

Papachristodoulou

et al. 2023

Medicina

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“…3) [2].Описано пацієнта 64 років з м'яким перебігом пневмонії COVID-19, потовщенням стінки клубової кишки та посиленням кровотоку в стінці жовчного міхура за нормальної товщини його стінки і виповненої сладжем порожнини (рис. 4)[6].Виявлено наявність COVID-19 у стінці жовчного міхура (qrt-RCR). При цьому розвивається клініка гострого холециститу, а радіологічно виявляють потовщення стінки жовчного міхура і перивезикулярну рідину (рис.…”

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SARS-CoV-2-related injury of biliary tract

Губергріц¹,

Ліневська²

2021

СГ

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Severe Acute Respiratory Syndrome Coronavirus‑2 (SARS‑CoV‑2), which causes coronavirus disease‑2019 (COVID‑19), affects several organs and systems. The ways of the virus penetration into tissues have been studied. Liver is affected in 15 — 53 % of cases. Data on the RNA‑seq sequencing in the Human Protein Atlas database confirm the expression of ACE2 (angiotensin 2 converting enzyme receptor) in the liver and epithelium of the bile ducts and gallbladder. At the same time, a high frequency of ACE2 expression is observed only in cholangiocytes, but not in hepatocytes, Kupffer cells or endothelial cells. The amount of ACE2 in bile duct cells is significantly higher than in hepatocytes, and is comparable to the level in type 2 alveolar cells in the lungs, which makes the biliary tract a potential target for the virus.Binding of SARS‑CoV‑2 to gallbladder epithelial cells can lead to mucosal inflammation. A systematic review describes the formation of bile clots in small bile ducts. Presence of COVID‑19 in the wall of the gallbladder (qrt‑RCR) has been revealed. With this, acute cholecystitis develops clinically, and radiological investigations show thickening of the gallbladder wall, biliary sludge and perivesicular fluid. Onset of acute gangrenous cholecystitis as a late complication of COVID‑19 infection is described. Histologically, inflammatory infiltrates are found in the gallbladder wall, which diffusely affect medium‑sized arteries with obliteration of their lumen, ischemia of the bladder wall; the perineural inflammation take place. These features indicate vasculitis with thrombosis.Thus, despite the theoretical information about the biliary tract injury by the COVID‑19 virus, this aspect of the infection has not been clinically studied, and the published papers are limited to the description of single clinical cases. In our opinion, a deeper and long‑term study of the biliary tract pathology in COVID‑19 infection is needed to provide rationale for the treatment with ursodeoxycholic acid.

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Abdominal imaging findings in patients with SARS-CoV-2 infection: a scoping review

2020

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Purpose This scoping review evaluated the currently available data related to abdominal imaging in the SARS-CoV-2 infection. Method A systematic review of MEDLINE, EMBASE, SCOPUS, and Web of Science was performed from inception to July 15, 2020 using PRISMA-ScR guidelines. The review included case reports and series discussing radiologic manifestations of SARS-CoV-2 infection in abdominal imaging studies.

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Abdominal Presentation of COVID-19

Cited by 7 publications

References 6 publications

Gastrointestinal Imaging Findings in the Era of COVID-19: A Pictorial Review

Gastrointestinal Imaging Findings in the Era of COVID-19: A Pictorial Review

SARS-CoV-2-related injury of biliary tract

Abdominal imaging findings in patients with SARS-CoV-2 infection: a scoping review

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