Abdominal pain in a patient with sickle cell disease with multiple complications

Abstract

Sickle cell disease is an inherited autosomal recessive hemoglobinopathy. Acute abdominal pain is the cause of hospitalization in 10% of patients with sickle cell disease and usually occurs during vaso-occlusion or distal tissue ischemia. Determining the etiology of abdominal pain is very difficult in these patients because it is associated with several rare diagnoses, such as pancreatitis and splenic abscess in some patients. We represent a 14-year-old boy with sickle cell disease who was hospitalized due to acute abdominal pain and indicated multiple and scarce disturbances in the spleen and hepatobiliary system.

Gastroduodenal Perforation in a Child With Sickle Cell Anemia: A Case Report

“…This report was of a rare complication of sickle cell anemia, namely of GDP, in a 12-year-old boy. One of the most common symptoms of sickle cell anemia as a hemoglobinopathy is abdominal pain (3). Nearly 10% of these patients are hospitalized annually with abdominal pain.…”

“…Secondary gastroduodenal perforation (GDP) may rarely cause by some diseases such as sickle cell anemia. One of the common symptoms in these patients is abdominal pain, attributed to circulatory stasis and vascular occlusion (2,3). There are only a few reports regarding GDP in children with sickle cell anemia.…”

Principais manifestações hepáticas na doença falciforme

“…Os pacientes com colelitíase costumam ser assintomáticos, mas quando sintomáticos, a dor abdominal é o sintoma mais comum, podendo ser em região epigástrica ou em quadrante superior direito (Mehrabani et al, 2019). Geralmente, a colelitíase passa despercebida exceto quando há colecistite aguda ou coledocolitíase.…”