Abdominal CT findings of disseminated Mycobacterium avium-intracellulare in AIDS

Nyberg, David A.; Federle, Michael P.; Jeffrey, R. Brooke; Bottles, Kent; Wofsy, Constance B.

doi:10.2214/ajr.145.2.297

Cited by 86 publications

(23 citation statements)

References 11 publications

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“…In addition, mycobacterial lesions in the abdominal lymph nodes of patients with disseminated MAC infection are not always detectable. Nyberg et al reported that mycobacterial abdominal lymphatic lesions were detected in 14 of 17 cases of disseminated MAC infection (11). These findings suggest that the isolated lesion observed in this case was possibly a consequence of transient bacteremia occurring prior to antimycobacterial treatment.…”

Section: Discussionsupporting

confidence: 50%

Acquired Immune-deficiency Syndrome with Focal Onset of <i>Mycobacterium avium</i> Infection Displaying a Histological/Genetic Pattern of Disseminated Mycobacteria

et al. 2012

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A 66-year-old man with human immunodeficiency virus (HIV) infection was admitted for treatment of Pneumocystis pneumonia. Upon admission, a tumor mass adjacent to the thoracic descending aorta was revealed on computed tomography. Histology revealed an exudative granuloma with histiocytes packed with numerous acid-fast bacilli. Mycobacterium avium was isolated from the tissue. A genetic examination of the isolates demonstrated this strain to be located in the cluster consisting of strains that cause systemic infection. The patient's baseline CD4 + cell count was 9/μL and the HIV-RNA viral load was 43,800 copies/mL. This case suggests the possibility of a localized onset of disseminated M. avium infection.

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Section: Discussionsupporting

confidence: 50%

Acquired Immune-deficiency Syndrome with Focal Onset of <i>Mycobacterium avium</i> Infection Displaying a Histological/Genetic Pattern of Disseminated Mycobacteria

et al. 2012

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“…Abdominal sonography, usually performed with a 3.5 Mhz transducer, has proven useful in the diagnosis of intraabdominal and retroperitoneal lesions in HIVinfected patients with prolonged fever, the rate of detection of focal lesions of the spleen in these patients using this method being 1-2% [1][2][3]. Computerized tomography (CT) is also a sensitive method for detecting abdominal abnormalities [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Etiology, Clinical Features and Outcome of Splenic Microabscesses in HIV-Infected Patients with Prolonged Fever

Bernabéu-Wittel

Villanueva

Pachón

et al. 1999

EJCMID

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A prospective study was conducted to determine the etiology, clinical features, and outcome in a series of 32 consecutively enrolled HIV-infected patients with prolonged fever in whom high resolution (7.5 Mhz) sonography revealed multiple splenic microabscesses. Conventional (3.5 Mhz) sonography showed no splenic abnormalities in any patients. The diagnoses were: tuberculosis (14), visceral leishmaniasis (7), disseminated Mycobacterium avium complex infection (5), Salmonella spp. bacteremia (2), lymphoma (2), disseminated Rhodococcus equi infection (1), disseminated Candida krusei infection (1) and Pneumocystis carinii pneumonia (1). Twenty-eight patients were followed up for six months and four were lost to follow-up. In 16 patients with a clinical cure and microbiological eradication, the findings on follow-up high resolution sonography were normal, and in two patients the microabscesses persisted; ten patients died. In conclusion, the findings suggest splenic microabscesses may be a frequent condition in HIV-infected patients with prolonged fever, being an unspecific manifestation of the opportunistic diseases causing fever of unknown origin in this population. They cannot be detected by conventional abdominal sonography, whereas high resolution sonography is a useful technique for their detection and follow-up.

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“…18,19 Our experience with ultrasonographic studies in 200 patients with AIDS suggests that bulky intra-abdominal adenopathy associated with focal splenic involvement is more frequently secondary to tuberculosis. 20 Hepatomegaly, together with diffusely increased echogenicity of the hepatic parenchyma, are ultrasonographic findings described in liver involvement in disseminated miliary tuberculosis.…”

Section: Discussionmentioning

confidence: 99%

Abdominal ultrasound findings of disseminated tuberculosis in AIDS

Monill-Serra

Martínez-Noguera

Montserrat

et al. 1997

J. Clin. Ultrasound

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Abdominal CT findings of disseminated Mycobacterium avium-intracellulare in AIDS

Cited by 86 publications

References 11 publications

Acquired Immune-deficiency Syndrome with Focal Onset of <i>Mycobacterium avium</i> Infection Displaying a Histological/Genetic Pattern of Disseminated Mycobacteria

Acquired Immune-deficiency Syndrome with Focal Onset of <i>Mycobacterium avium</i> Infection Displaying a Histological/Genetic Pattern of Disseminated Mycobacteria

Etiology, Clinical Features and Outcome of Splenic Microabscesses in HIV-Infected Patients with Prolonged Fever

Abdominal ultrasound findings of disseminated tuberculosis in AIDS

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