Abstract:BackgroundIn recent years, the increased prevalence of liver abnormalities in Psoriatic Arthritis (PsA) has acquired relevance. The liver dysfunction in PsA might be induced by inflammatory components in parallel with the presence of metabolic complications or due to the potential hepatotoxicity of the treatments administered.Objectives1) to analyze the impact of PsA serum on hepatocytes and 2) to investigate the effect of methotrexate, anti-PDE-4, and tofacitinib on hepatocytes treated with PsA serum.Methodss… Show more
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